Difference between revisions of "Bizarre parosteal osteochondromatous proliferation"
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| Line 15: | Line 15: | ||
| Gross = | | Gross = | ||
| Grossing = | | Grossing = | ||
| Site = | | Site =Hands, feet | ||
| Assdx = | | Assdx = | ||
| Syndromes = | | Syndromes = | ||
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==Microscopic== | ==Microscopic== | ||
Disorganized cellular cartilage with a blue tint and patchy ossification matures into disorganized bone. A proliferation of fibroblasts surrounds the lesion and occupies intertrabecular spaces. | Disorganized cellular cartilage with a blue tint and patchy ossification matures into disorganized bone. A proliferation of fibroblasts surrounds the lesion and occupies intertrabecular spaces. | ||
==Images== | |||
*BPOP[http://www.webpathology.com/images/noimage.gif] | |||
*BPOP[http://webpathology.com/images/noimage.gif] | |||
*BPOP[http://www.webpathology.com/images/noimage.gif] | |||
*BPOP[http://pathologyoutlines.com/wick/bizarre%20parosteal%20osteochondromatous%20proliferation%20(bpop-%20no.jpg] | |||
==DDX== | ==DDX== | ||
* | *Periosteal chondrosarcoma | ||
*Periosteal chondroma | *Periosteal chondroma | ||
*Low grade parosteal osteosarcoma | |||
*Osteochondroma | *Osteochondroma | ||
==Diangostic categories== | ==Diangostic categories== | ||
| Line 72: | Line 78: | ||
==See also== | ==See also== | ||
*[http://www.pathologyoutlines.com/topic/bonebizarreparosteal.html] | |||
==References== | ==References== | ||
{{Reflist|1}} | {{Reflist|1}} | ||
Revision as of 11:51, 16 October 2014
| Bizarre parosteal osteochondromatous proliferation | |
|---|---|
| Diagnosis in short | |
|
| |
| Synonyms | Nora lesion |
| Site | Hands, feet |
|
| |
General
A distinctive osteochondromatous proliferation of hands and feet.
Population
- Young adults
- 20s-30s
Location
Hands and feet
Radiology
Marginated wide based bony growth projecting into the soft tissues[1]
Gross
- Nodule covered with glistening cartilage
Microscopic
Disorganized cellular cartilage with a blue tint and patchy ossification matures into disorganized bone. A proliferation of fibroblasts surrounds the lesion and occupies intertrabecular spaces.
Images
![[1]](http://www.webpathology.com/images/noimage.gif){kind=link}
![[2]](http://webpathology.com/images/noimage.gif){kind=link}
![[4]](http://pathologyoutlines.com/wick/bizarre%20parosteal%20osteochondromatous%20proliferation%20(bpop-%20no.jpg){kind=link}
DDX
- Periosteal chondrosarcoma
- Periosteal chondroma
- Low grade parosteal osteosarcoma
- Osteochondroma
Diangostic categories
- Cartilaginous neoplasms
- Osteocartilaginous neoplasms
Stains
IHC
Molecular
t(1:17)(q32;q21)[2]
Sign out
Prognosis
- Benign
- Locally aggressive
See also
References
- ↑ http://radiopaedia.org/articles/bizarre-parosteal-osteochondromatous-proliferation
- ↑ Kuruvilla, S.; Marco, R.; Raymond, AK.; Al-Ibraheemi, A.; Tatevian, N. (2011). "BizarreParosteal Osteochondromatous Proliferation (Nora's lesion) with translocation t(1;17)(q32;q21): a case report and role of cytogenetic studies on diagnosis.". Ann Clin Lab Sci 41 (3): 285-7. PMID 22075515.