Difference between revisions of "Pineal gland"
Jump to navigation
Jump to search
(create) |
(→Pathology: more) |
||
| Line 5: | Line 5: | ||
*Cellular. | *Cellular. | ||
== | ==Overview== | ||
Tumours:<ref name=pmid20971711>{{cite journal |author=Gaillard F, Jones J |title=Masses of the pineal region: clinical presentation and radiographic features |journal=Postgrad Med J |volume=86 |issue=1020 |pages=597–607 |year=2010 |month=October |pmid=20971711 |doi=10.1136/pgmj.2009.087460 |url=}}</ref> | |||
*Primary pineal tumours ~15% of (pineal) tumours. | *Primary pineal tumours ~15% of (pineal) tumours - benign to malignant:<ref name=pmid21057132>{{cite journal |author=Smith AB, Rushing EJ, Smirniotopoulos JG |title=From the archives of the AFIP: lesions of the pineal region: radiologic-pathologic correlation |journal=Radiographics |volume=30 |issue=7 |pages=2001–20 |year=2010 |month=November |pmid=21057132 |doi=10.1148/rg.307105131 |url=}}</ref> | ||
**Pineocytoma. | **Pineocytoma. | ||
**Pineal parenchymal tumor of intermediate differentiation. | |||
**Pineoblastoma. | **Pineoblastoma. | ||
*Germ cell tumours | *Germ cell tumours: | ||
**Germinoma ~ 50% of (pineal) tumours. | **Germinoma ~ 50% of (pineal) tumours. | ||
**Teratoma ~ 15% of tumours. | **Teratoma ~ 15% of tumours. | ||
**Choricocarcinoma ~ 5% of tumours. | **Choricocarcinoma ~ 5% of tumours. | ||
*Others | *Others: | ||
**Direct invasion/extension from surrounding structures ( | **Direct invasion/extension from surrounding structures (astrocytomas). | ||
**Metastases. | **Metastases. | ||
**Lipomas. | |||
**Meningiomas. | |||
==Primary pineal tumours== | |||
Range from benign to malignant. | |||
==Pineocytoma== | |||
Features: | |||
*Cytologically benign cells (uniform size of nuclei, regular nuclear membrane, light chromatin). | |||
*Pineocytomatous/neurocytic rosette.<ref name=pmid16551982>{{cite journal |author=Wippold FJ, Perry A |title=Neuropathology for the neuroradiologist: rosettes and pseudorosettes |journal=AJNR Am J Neuroradiol |volume=27 |issue=3 |pages=488–92 |year=2006 |month=March |pmid=16551982 |doi= |url=}}</ref> | |||
**Similar to Homer-Wright rosette - neuropil centre larger. | |||
**Rosette with a meshwork of fibers (neuropil) at the centre. | |||
==See also== | ==See also== | ||
Revision as of 03:10, 4 December 2010
The pineal gland is thingy that is most noted for the fact that it calcifies with age.
Normal histology
- Cellular.
Overview
Tumours:[1]
- Primary pineal tumours ~15% of (pineal) tumours - benign to malignant:[2]
- Pineocytoma.
- Pineal parenchymal tumor of intermediate differentiation.
- Pineoblastoma.
- Germ cell tumours:
- Germinoma ~ 50% of (pineal) tumours.
- Teratoma ~ 15% of tumours.
- Choricocarcinoma ~ 5% of tumours.
- Others:
- Direct invasion/extension from surrounding structures (astrocytomas).
- Metastases.
- Lipomas.
- Meningiomas.
Primary pineal tumours
Range from benign to malignant.
Pineocytoma
Features:
- Cytologically benign cells (uniform size of nuclei, regular nuclear membrane, light chromatin).
- Pineocytomatous/neurocytic rosette.[3]
- Similar to Homer-Wright rosette - neuropil centre larger.
- Rosette with a meshwork of fibers (neuropil) at the centre.
See also
References
- ↑ Gaillard F, Jones J (October 2010). "Masses of the pineal region: clinical presentation and radiographic features". Postgrad Med J 86 (1020): 597–607. doi:10.1136/pgmj.2009.087460. PMID 20971711.
- ↑ Smith AB, Rushing EJ, Smirniotopoulos JG (November 2010). "From the archives of the AFIP: lesions of the pineal region: radiologic-pathologic correlation". Radiographics 30 (7): 2001–20. doi:10.1148/rg.307105131. PMID 21057132.
- ↑ Wippold FJ, Perry A (March 2006). "Neuropathology for the neuroradiologist: rosettes and pseudorosettes". AJNR Am J Neuroradiol 27 (3): 488–92. PMID 16551982.