Difference between revisions of "Squamous cell carcinoma of the esophagus"
(split out) |
m (→Sign out) |
||
| Line 33: | Line 33: | ||
==Sign out== | ==Sign out== | ||
<pre> | <pre> | ||
ESOPHAGUS, BIOPSY: | |||
- INVASIVE SQUAMOUS CELL CARCINOMA, KERATINIZING, MODERATELY DIFFERENTIATED. | - INVASIVE SQUAMOUS CELL CARCINOMA, KERATINIZING, MODERATELY DIFFERENTIATED. | ||
Revision as of 16:01, 20 February 2014
Squamous cell carcinoma of the esophagus is a relatively uncommon form of esophageal cancer.
It is also known as esophageal squamous cell carcinoma, abbreviated esophageal SCC.
Squamous cell carcinoma, also squamous carcinoma, is discussed in general terms in the squamous cell carcinoma article.
General
- Like squamous cell carcinoma elsewhere.
Risk factors:[1]
- Alcohol consumption.
- Tobacco use.
- Food with nitrosamines.
- Burning-hot beverages.
Note:
- Reflux is not a risk factor for esophageal SCC.
- It is a risk factor indirectly for esophageal adenocarcinoma.
Microscopic
- See Squamous carcinoma.
Note:
- Just to make things confusing, the Staging of early SCC differs from that of early adenocarcinoma!
DDx:
Images
Sign out
ESOPHAGUS, BIOPSY: - INVASIVE SQUAMOUS CELL CARCINOMA, KERATINIZING, MODERATELY DIFFERENTIATED. COMMENT: Benign squamous epithelium at least partially overlies the invasive squamous cell carcinoma; this may mask the true extent of the lesion on endoscopy.
Micro
The sections show a squamous mucosa with focal moderate atypia of the squamous cells, keratinization and easily identified mitotic figures. The atypical cells are partially covered by benign squamous cells, and there is a very sharp transition between the cells with atypia and those without. The atypical squamous cells extend into the subepithelial tissue in irregularly shaped nests and cords. A small amount of benign muscle is present.
See also
References
- ↑ Lefkowitch, Jay H. (2006). Anatomic Pathology Board Review (1st ed.). Saunders. pp. 104 Q1. ISBN 978-1416025887.
- ↑ Terada, T. (2013). "A clinicopathologic study of esophageal 860 benign and malignant lesions in 910 cases of consecutive esophageal biopsies.". Int J Clin Exp Pathol 6 (2): 191-8. PMID 23330004.