Difference between revisions of "Squamous cell carcinoma of the esophagus"

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#redirect [[Esophagus#Squamous_cell_carcinoma_of_the_esophagus]]
'''Squamous cell carcinoma of the esophagus''' is a relatively uncommon form of esophageal cancer.


It is also known as '''esophageal squamous cell carcinoma''', abbreviated '''esophageal SCC'''.
''Squamous cell carcinoma'', also ''squamous carcinoma'', is discussed in general terms in the ''[[squamous cell carcinoma]]'' article.
==General==
*Like squamous cell carcinoma elsewhere.
Risk factors:<ref name=Ref_APBR104>{{Ref APBR|104 Q1}}</ref>
*[[Ethanol abuse|Alcohol consumption]].
*[[Smoking|Tobacco use]].
*Food with nitrosamines.
*Burning-hot beverages.
Note:
*Reflux is ''not'' a risk factor for esophageal SCC.
**It is a risk factor indirectly for [[esophageal adenocarcinoma]].
==Microscopic==
:See ''[[Squamous carcinoma]]''.
Note:
*Just to make things confusing, the ''Staging'' of early SCC differs from that of early adenocarcinoma!
DDx:
*[[Squamous dysplasia of the esophagus]].
===Images===
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544238/figure/fig08/ Carcinoma in situ (nih.gov)].<ref name=pmid23330004>{{Cite journal  | last1 = Terada | first1 = T. | title = A clinicopathologic study of esophageal 860 benign and malignant lesions in 910 cases of consecutive esophageal biopsies. | journal = Int J Clin Exp Pathol | volume = 6 | issue = 2 | pages = 191-8 | month =  | year = 2013 | doi =  | PMID = 23330004 }}</ref>
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544238/figure/fig09/ Squamous cell carcinoma of the esophagus (nih.gov)].
==Sign out==
<pre>
ESOPHGAUS, BIOPSY:
- INVASIVE SQUAMOUS CELL CARCINOMA, KERATINIZING, MODERATELY DIFFERENTIATED.
COMMENT:
Benign squamous epithelium at least partially overlies the invasive squamous
cell carcinoma; this may mask the true extent of the lesion on endoscopy.
</pre>
===Micro===
The sections show a squamous mucosa with focal moderate atypia of the squamous cells,
keratinization and easily identified mitotic figures. The atypical cells are partially
covered by benign squamous cells, and there is a very sharp transition between the cells
with atypia and those without. The atypical squamous cells extend into the subepithelial tissue in irregularly shaped nests and cords. A small amount of benign muscle is present.
==See also==
*[[Esophagus]].
*[[Squamous cell carcinoma]].
==References==
{{Reflist|2}}
[[Category:Esophagus]]
[[Category:Diagnosis]]
[[Category:Diagnosis]]

Revision as of 04:14, 17 February 2014

Squamous cell carcinoma of the esophagus is a relatively uncommon form of esophageal cancer.

It is also known as esophageal squamous cell carcinoma, abbreviated esophageal SCC.

Squamous cell carcinoma, also squamous carcinoma, is discussed in general terms in the squamous cell carcinoma article.

General

  • Like squamous cell carcinoma elsewhere.

Risk factors:[1]

Note:

Microscopic

See Squamous carcinoma.

Note:

  • Just to make things confusing, the Staging of early SCC differs from that of early adenocarcinoma!

DDx:

Images

Sign out

ESOPHGAUS, BIOPSY:
- INVASIVE SQUAMOUS CELL CARCINOMA, KERATINIZING, MODERATELY DIFFERENTIATED.

COMMENT:
Benign squamous epithelium at least partially overlies the invasive squamous 
cell carcinoma; this may mask the true extent of the lesion on endoscopy.

Micro

The sections show a squamous mucosa with focal moderate atypia of the squamous cells, keratinization and easily identified mitotic figures. The atypical cells are partially covered by benign squamous cells, and there is a very sharp transition between the cells with atypia and those without. The atypical squamous cells extend into the subepithelial tissue in irregularly shaped nests and cords. A small amount of benign muscle is present.

See also

References

  1. ↑ Lefkowitch, Jay H. (2006). Anatomic Pathology Board Review (1st ed.). Saunders. pp. 104 Q1. ISBN 978-1416025887.
  2. ↑ Terada, T. (2013). "A clinicopathologic study of esophageal 860 benign and malignant lesions in 910 cases of consecutive esophageal biopsies.". Int J Clin Exp Pathol 6 (2): 191-8. PMID 23330004.
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