Difference between revisions of "Peripheral nerve sheath tumours"
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'''Peripheral nerve sheath tumours''' are | '''Peripheral nerve sheath tumours''', abbreviated '''PNSTs''', are common in [[neuropathology]] and occasionally show-up elsewhere. A very common PNST is the [[Peripheral nerve sheath tumours#Schwannoma|schwannoma]]. | ||
==Classification== | ==Classification== | ||
Revision as of 18:10, 24 November 2010
Peripheral nerve sheath tumours, abbreviated PNSTs, are common in neuropathology and occasionally show-up elsewhere. A very common PNST is the schwannoma.
Classification
A classification:[1]
- Benign:
- Schwannoma.
- Neurofibroma.
- Perineurioma.
- Traumatic neuroma.
- Malignant:
- Malignant peripheral nerve sheath tumour (MPNST).
Schwannoma
General
- A common neuropathology tumour that occasionally shows-up elsewhere.
- Tumour of tissue surrounding a nerve.
- Axons adjacent to the tumour are normal... but may be compressed.
Microscopic
Features:[1]
- Antoni tissue (type A and type B).
- Verocay bodies - paucinuclear area surrounded by nuclei.
Notes:
- Tumour does not smear well.[2]
Antoni A
- Cellular.
- 'Fibrillary, polar, elongated'.
Comment: May look somewhat like scattered matchsticks.
Antoni B
- Loose microcystic tissue.
- Adjacent to Antoni A.
Micrographs:
See also
References
- ↑ 1.0 1.1 Wippold FJ, Lubner M, Perrin RJ, Lämmle M, Perry A (October 2007). "Neuropathology for the neuroradiologist: Antoni A and Antoni B tissue patterns". AJNR Am J Neuroradiol 28 (9): 1633–8. doi:10.3174/ajnr.A0682. PMID 17893219. http://www.ajnr.org/cgi/reprint/28/9/1633.
- ↑ MUN. 24 November 2010.