Liver pathology: Difference between revisions
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Microvesicular steatosis DDx:<ref name=pmid2177300>PMID 2177300</ref> | Microvesicular steatosis DDx:<ref name=pmid2177300>PMID 2177300</ref> | ||
*Acute fatty liver of pregnancy, | *Acute fatty liver of pregnancy, | ||
*Reye's syndrome | *Reye's syndrome. | ||
*Drug toxicity: | *Drug toxicity: | ||
**Sodium valproate toxicity | **Sodium valproate toxicity. | ||
**High-dose tetracycline toxicity. | **High-dose tetracycline toxicity. | ||
*Jamaican vomiting sickness | *Jamaican vomiting sickness. | ||
*Congenital defects of urea cycle enzymes. | *Congenital defects of urea cycle enzymes. | ||
Less common causes: | Less common causes: | ||
*Alcoholism | *Alcoholism. | ||
*Hepatitis D | *Hepatitis D. | ||
*Weird stuff: | *Weird stuff: | ||
**Congenital defects of fatty acid beta oxidation, | **Congenital defects of fatty acid beta oxidation, | ||
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The classic causes of microvesicular steatosis are:<ref>[http://www.mailman.srv.ualberta.ca/pipermail/patho-l/1996-June/001788.html http://www.mailman.srv.ualberta.ca/pipermail/patho-l/1996-June/001788.html]</ref> | The classic causes of microvesicular steatosis are:<ref>[http://www.mailman.srv.ualberta.ca/pipermail/patho-l/1996-June/001788.html http://www.mailman.srv.ualberta.ca/pipermail/patho-l/1996-June/001788.html]</ref> | ||
*Fatty liver of pregnancy. | *Fatty liver of pregnancy. | ||
*Aspirin (Reye's syndrome). | |||
*Tetracycline. | |||
It was once thought that all other causes of fatty liver produce macrovesicular steatosis. | It was once thought that all other causes of fatty liver produce macrovesicular steatosis. | ||