Difference between revisions of "Sinus histiocytosis"
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'''Sinus histiocytosis''' | '''Sinus histiocytosis''', abbreviated '''SH''', is a common finding in [[lymph nodes]]. | ||
It should '''not''' be confused with [[Rosai-Dorfman disease]] (also known as ''sinus histiocytosis and massive lymphadenopathy''). | |||
==General== | |||
*Benign. | |||
*Non-specific finding. | |||
==Microscopic== | |||
Features:<ref name=Ref_ILNP179>{{Ref_ILNP|179}}</ref> | |||
*Sinuses distended with histiocytes - '''key feature'''. | |||
*[[Plasma cell]]s increased. | |||
DDx: | |||
*[[Rosai-Dorfman disease]] - histiocyte nuclei large (~2-3x lymphocyte) and round with a prominent nucleoli. | |||
*[[Dermatopathic lymphadenopathy]] - histiocytes have (melanin) pigment. | |||
===Images=== | |||
<gallery> | |||
Image: Sinus histiocytosis -- intermed mag.jpg | SH - intermed. mag. | |||
Image: Sinus histiocytosis -- high mag.jpg | SH - high mag. | |||
Image: Sinus histiocytosis - deep -- high mag.jpg | SH - high mag. | |||
</gallery> | |||
==Sign out== | |||
*The finding is often ignored; may be signed out as ''morphologically benign lymph nodes''. | |||
==See also== | ==See also== | ||
Revision as of 00:21, 1 December 2013
Sinus histiocytosis, abbreviated SH, is a common finding in lymph nodes.
It should not be confused with Rosai-Dorfman disease (also known as sinus histiocytosis and massive lymphadenopathy).
General
- Benign.
- Non-specific finding.
Microscopic
Features:[1]
- Sinuses distended with histiocytes - key feature.
- Plasma cells increased.
DDx:
- Rosai-Dorfman disease - histiocyte nuclei large (~2-3x lymphocyte) and round with a prominent nucleoli.
- Dermatopathic lymphadenopathy - histiocytes have (melanin) pigment.
Images
SH - intermed. mag.
SH - high mag.
SH - high mag.
Sign out
- The finding is often ignored; may be signed out as morphologically benign lymph nodes.
See also
- ↑ Ioachim, Harry L; Medeiros, L. Jeffrey (2008). Ioachim's Lymph Node Pathology (4th ed.). Lippincott Williams & Wilkins. pp. 179. ISBN 978-0781775960.