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Difference between revisions of "Renal oncocytoma"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Renal_oncocytoma2.jpg | |||
| Width = | |||
| Caption = Renal oncocytoma. [[H&E stain]]. | |||
| Micro = abundant eosinophilic cytoplasm - slightly granular, cells arranged in nests, nuclei uniform and round without significant pleomorphism | |||
| Subtypes = | |||
| LMDDx = [[chromophobe renal cell carcinoma]] eosinophilic variant, [[clear cell renal cell carcinoma]] eosinophilic variant, [[papillary renal cell carcinoma]] oncocytic variant | |||
| Stains = [[Hale's colloidal iron]] -ve | |||
| IHC = CK7 -ve/cytoplasmic +ve | |||
| EM = abundant mitochondria | |||
| Molecular = | |||
| IF = | |||
| Gross = mass, mahogany brown +/- central scar | |||
| Grossing = | |||
| Site = [[kidney]] - see [[kidney tumours]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = | |||
| Bloodwork = | |||
| Rads = central scar | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = other [[kidney tumours]] | |||
}} | |||
'''Renal oncocytoma''' is a benign [[kidney tumour]] that is removed to exclude malignancy. | '''Renal oncocytoma''' is a benign [[kidney tumour]] that is removed to exclude malignancy. | ||
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==Gross== | ==Gross== | ||
* | *Mass, mahogany brown. | ||
*1/3 have a characteristic central scar.<ref name=Ref_GUP302>{{Ref GUP|302}}</ref> | **Well circumscribed. | ||
**1/3 have a characteristic central scar.<ref name=Ref_GUP302>{{Ref GUP|302}}</ref> | |||
===Image=== | ===Image=== | ||
| Line 36: | Line 66: | ||
Image:Renal_oncocytoma4.jpg | Oncocytoma - low mag. (WC/Nephron) | Image:Renal_oncocytoma4.jpg | Oncocytoma - low mag. (WC/Nephron) | ||
</gallery> | </gallery> | ||
== | ==Stains== | ||
*[[Hale's colloidal iron]] -ve | *[[Hale's colloidal iron]] -ve. | ||
**[[ChRCC]] +ve (blue granular cytoplasmic). | **[[ChRCC]] +ve (blue granular cytoplasmic). | ||