Difference between revisions of "Talk:Neuropathology tumours"
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==Meningioma== | ==Meningioma== | ||
===Microscopic=== | ===Microscopic=== | ||
The microscopic section shows a moderately cellular with lesion with prominent whorls, thick-walled blood vessels and focal calcifications. | The microscopic '''section/sections''' shows a moderately cellular with lesion with prominent whorls, thick-walled blood vessels and focal calcifications. | ||
There are less than 4 mitoses / HPF, where 1 HPF is approximately 0.2376 mm^2. There are no macronucleoli, no sheeting architecture, no hypercellularity, and no spontaneous necrosis. The cells of the lesion do not have a high nuclear-to-cytoplasmic ratio. | There are less than 4 mitoses / HPF, where 1 HPF is approximately 0.2376 mm^2. There are no macronucleoli, no sheeting architecture, no hypercellularity, and no spontaneous necrosis. The cells of the lesion do not have a high nuclear-to-cytoplasmic ratio. | ||
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===Final diagnosis=== | ===Final diagnosis=== | ||
MENINGIOMA, GRADE 1. | MENINGIOMA, GRADE 1. | ||
==Anaplastic astrocytoma== | |||
===Microscopic=== | |||
The microscopic '''section/sections''' shows white matter with tumour. The tumour cell nuclei are oblong and have a marked irregular profile and occasionally eosinophilic cytoplasm. Mitoses are '''rare/common'''. There is no necrosis and no microvascular proliferation. Immunohistochemistry shows GFAP staining of the perikaryon in cytologically malignant cells. '''Occasional/Many/All''' tumour cells stain for p53. The Ki-67 is positive in approximately '''X%''' of tumour cells. | |||
===Final diagnosis=== | |||
ANAPLASTIC ASTROCYTOMA, WHO GRADE 3. | |||
==Oligodendroglioma== | |||
===Microscopic=== | |||
The microscopic '''section/sections''' shows regularly distributed cells with round nuclei that are surrounded by clear halos. No mitoses are present. Microvascular proliferation is not seen. The nuclear atypia is mild-to-moderate. There is no nuclear overlapping. | |||
===Final diagnosis=== | |||
OLIGODENDROGLIOMA, WHO GRADE 2. | |||
Revision as of 03:15, 4 November 2010
Meningioma
Microscopic
The microscopic section/sections shows a moderately cellular with lesion with prominent whorls, thick-walled blood vessels and focal calcifications.
There are less than 4 mitoses / HPF, where 1 HPF is approximately 0.2376 mm^2. There are no macronucleoli, no sheeting architecture, no hypercellularity, and no spontaneous necrosis. The cells of the lesion do not have a high nuclear-to-cytoplasmic ratio.
Final diagnosis
MENINGIOMA, GRADE 1.
Anaplastic astrocytoma
Microscopic
The microscopic section/sections shows white matter with tumour. The tumour cell nuclei are oblong and have a marked irregular profile and occasionally eosinophilic cytoplasm. Mitoses are rare/common. There is no necrosis and no microvascular proliferation. Immunohistochemistry shows GFAP staining of the perikaryon in cytologically malignant cells. Occasional/Many/All tumour cells stain for p53. The Ki-67 is positive in approximately X% of tumour cells.
Final diagnosis
ANAPLASTIC ASTROCYTOMA, WHO GRADE 3.
Oligodendroglioma
Microscopic
The microscopic section/sections shows regularly distributed cells with round nuclei that are surrounded by clear halos. No mitoses are present. Microvascular proliferation is not seen. The nuclear atypia is mild-to-moderate. There is no nuclear overlapping.
Final diagnosis
OLIGODENDROGLIOMA, WHO GRADE 2.