Difference between revisions of "Diverticular disease"
Jump to navigation
Jump to search
m |
|||
| Line 15: | Line 15: | ||
| Grossing = | | Grossing = | ||
| Site = [[colon]], other sites | | Site = [[colon]], other sites | ||
| Assdx = diverticulitis, peritonitis | | Assdx = diverticulitis, peritonitis, diverticular-associated [[colitis]] | ||
| Syndromes = | | Syndromes = | ||
| Clinicalhx = | | Clinicalhx = | ||
| Line 26: | Line 26: | ||
| Prognosis = | | Prognosis = | ||
| Other = | | Other = | ||
| ClinDDx = [[colorectal carcinoma]] | | ClinDDx = [[colorectal carcinoma]] | ||
}} | }} | ||
'''Diverticular disease''', also '''diverticulosis''', is a common disease of the [[colon]]. Inflammation of diverticula is known as '''diverticulitis'''. | '''Diverticular disease''', also '''diverticulosis''', is a common disease of the [[colon]]. Inflammation of diverticula is known as '''diverticulitis'''. | ||
| Line 53: | Line 53: | ||
*Mucosa/submucosa invagination into the musuclaris propria (MP). | *Mucosa/submucosa invagination into the musuclaris propria (MP). | ||
**At the site the blood vessels supplying the mucosa and submucosa penetrate the MP.<ref name=pmid18936652>{{Cite journal | last1 = West | first1 = AB. | title = The pathology of diverticulitis. | journal = J Clin Gastroenterol | volume = 42 | issue = 10 | pages = 1137-8 | month = | year = | doi = 10.1097/MCG.0b013e3181862a9f | PMID = 18936652 }}</ref> | **At the site the blood vessels supplying the mucosa and submucosa penetrate the MP.<ref name=pmid18936652>{{Cite journal | last1 = West | first1 = AB. | title = The pathology of diverticulitis. | journal = J Clin Gastroenterol | volume = 42 | issue = 10 | pages = 1137-8 | month = | year = | doi = 10.1097/MCG.0b013e3181862a9f | PMID = 18936652 }}</ref> | ||
DDx: | |||
*[[Colorectal carcinoma]] - may cause a stricture, usually obvious on microscopy. | |||
*[[Inflammatory bowel disease]]. | |||
===Images=== | ===Images=== | ||
Revision as of 22:07, 4 August 2013
| Diverticular disease | |
|---|---|
| Diagnosis in short | |
 Diverticulum. H&E stain. | |
|
| |
| LM | mucosa/submucosa invaginate into the musuclaris propria |
| Site | colon, other sites |
|
| |
| Associated Dx | diverticulitis, peritonitis, diverticular-associated colitis |
| Symptoms | usu. asymptomatic, diverticulitis presents with abdominal pain |
| Clin. DDx | colorectal carcinoma |
Diverticular disease, also diverticulosis, is a common disease of the colon. Inflammation of diverticula is known as diverticulitis.
General
- Very common.
- Typically seen in elderly patients - 50s and 60s.
Complications:
- Diverticulitis.
- Diverticular-associated colitis[1] - rare.
- Rectal biopsy to differentiate from ulcerative colitis.
Gross
- Corrugated - like cardboard.
- Wall thickening (reactive).[2]
Endoscopic image
Diverticular disease. (WC/Samir)
Grossing notes
Microscopic
Features:
- Mucosa/submucosa invagination into the musuclaris propria (MP).
- At the site the blood vessels supplying the mucosa and submucosa penetrate the MP.[3]
DDx:
- Colorectal carcinoma - may cause a stricture, usually obvious on microscopy.
- Inflammatory bowel disease.
Images
Diverticular disease. (WC)
www:
Sign out
RECTO-SIGMOID, LARGE BOWEL RESECTION: - PERFORATED DIVERTICULITIS WITH SEROSITIS AND ABSCESS FORMATION. - SUBMUCOSAL FIBROSIS. - ONE LYMPH NODE NEGATIVE FOR MALIGNANCY ( 0 POSITIVE / 1 ). - NEGATIVE FOR MALIGNANCY.
SIGMOID COLON, SIGMOIDECTOMY: - DIVERTICULAR DISEASE WITHOUT DIVERTICULITIS. - NEGATIVE FOR MALIGNANCY.
See also
References
- ↑ Mulhall, AM.; Mahid, SS.; Petras, RE.; Galandiuk, S. (Jun 2009). "Diverticular disease associated with inflammatory bowel disease-like colitis: a systematic review.". Dis Colon Rectum 52 (6): 1072-9. doi:10.1007/DCR.0b013e31819ef79a. PMID 19581849.
- ↑ Nicholson, BD.; Hyland, R.; Rembacken, BJ.; Denyer, M.; Hull, MA.; Tolan, DJ. (Aug 2011). "Colonoscopy for colonic wall thickening at computed tomography: a worthwhile pursuit?". Surg Endosc 25 (8): 2586-91. doi:10.1007/s00464-011-1591-7. PMID 21359889.
- ↑ West, AB.. "The pathology of diverticulitis.". J Clin Gastroenterol 42 (10): 1137-8. doi:10.1097/MCG.0b013e3181862a9f. PMID 18936652.
- ↑ URL: http://histology-group28.wikispaces.com/DigestiveSystemProject. Accessed on: 23 August 2011.