Difference between revisions of "Dermal scar"
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'''Dermal scar''', also simply '''scar''', is commonly seen in [[dermatopathology]]. It is also known a '''cicatrix'''. | |||
==General== | |||
*Previous surgery, biopsy, trauma. | |||
==Microscopic== | |||
Features: | |||
*Loss of dermal papilla. | |||
*Dense collagen - fibers run parallel to the dermal-epidermal (DE) junction<ref name=Ref_Derm499>{{Ref Derm|499}}</ref> - '''key feature'''. | |||
*Loss of adnexal structures. | |||
Other feature: | |||
*Thin-walled blood vessels. | |||
**Described as running perpendicular to the surface<ref name=Ref_Derm499>{{Ref Derm|499}}</ref> - this may not be apparent. | |||
Note: | |||
*There should not be any nuclear hyperchromasia or pleomorphism.<ref name=Ref_Derm479>{{Ref Derm|479}}</ref> | |||
DDx: | |||
*[[Malignant melanoma]], desmoplastic-neurotropic type - nuclear pleomorphism and/or hyperchromasia; may be focal.<ref name=Ref_Derm479>{{Ref Derm|479}}</ref> | |||
*[[Dermatofibroma]]. | |||
*Desmoplastic [[Spitz nevus]]. | |||
*Sclerosing [[blue nevus]]. | |||
===Image=== | |||
<gallery> | |||
Image:ScarHistology.JPG | Scar. (WC) | |||
</gallery> | |||
==IHC== | |||
*S100 focal/scattered +ve. | |||
**Desmoplastic melanoma strong +ve. | |||
*HMB-45 -ve. | |||
**Sclerosing blue nevus +ve. | |||
==Sign out== | |||
<pre> | |||
SKIN, LOWER MID BACK, RE-EXCISION: | |||
- DERMAL SCAR. | |||
- SOLAR ELASTOSIS. | |||
</pre> | |||
===Micro=== | |||
The sections show skin with a dermis with dense collagen fibres that run parallel to the skin surface without adnexal structures. The overlying dermal-epidermis interface lacks the typical undulation. | |||
==See also== | |||
*[[Non-malignant skin disease]]. | |||
*[[Dermatopathology]]. | |||
[[Category:Diagnosis]] | |||
[[Category:Dermatopathology]] | |||
Revision as of 18:01, 3 August 2013
Dermal scar, also simply scar, is commonly seen in dermatopathology. It is also known a cicatrix.
General
- Previous surgery, biopsy, trauma.
Microscopic
Features:
- Loss of dermal papilla.
- Dense collagen - fibers run parallel to the dermal-epidermal (DE) junction[1] - key feature.
- Loss of adnexal structures.
Other feature:
- Thin-walled blood vessels.
- Described as running perpendicular to the surface[1] - this may not be apparent.
Note:
- There should not be any nuclear hyperchromasia or pleomorphism.[2]
DDx:
- Malignant melanoma, desmoplastic-neurotropic type - nuclear pleomorphism and/or hyperchromasia; may be focal.[2]
- Dermatofibroma.
- Desmoplastic Spitz nevus.
- Sclerosing blue nevus.
Image
Scar. (WC)
IHC
- S100 focal/scattered +ve.
- Desmoplastic melanoma strong +ve.
- HMB-45 -ve.
- Sclerosing blue nevus +ve.
Sign out
SKIN, LOWER MID BACK, RE-EXCISION: - DERMAL SCAR. - SOLAR ELASTOSIS.
Micro
The sections show skin with a dermis with dense collagen fibres that run parallel to the skin surface without adnexal structures. The overlying dermal-epidermis interface lacks the typical undulation.
See also
- ↑ 1.0 1.1 Busam, Klaus J. (2009). Dermatopathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Saunders. pp. 499. ISBN 978-0443066542.
- ↑ 2.0 2.1 Busam, Klaus J. (2009). Dermatopathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Saunders. pp. 479. ISBN 978-0443066542.