Difference between revisions of "Epstein-Barr virus-associated smooth muscle tumour"
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==Microscopic== | ==Microscopic== | ||
Features: | Features:<ref name=pmid16330945/> | ||
*Spindle | *Smooth muscle lesion: | ||
**Spindle cells in a [[fascicular]] arrangement. | |||
**Usually minimal nuclear atypia and few mitoses. | |||
*Lymphocytes. | |||
DDx: | DDx: | ||
Revision as of 03:14, 4 March 2013
Epstein-Barr virus-associated smooth muscle tumour is a very uncommon soft tissue lesion.[1]
General
- Immunosuppressed individuals.
- Caused by Epstein-Barr virus.
Microscopic
Features:[1]
- Smooth muscle lesion:
- Spindle cells in a fascicular arrangement.
- Usually minimal nuclear atypia and few mitoses.
- Lymphocytes.
DDx:
IHC
- SMA +ve
- Desmin +ve/-ve.
- CD34 -ve.
- CD117 -ve.
References
- ↑ 1.0 1.1 Deyrup, AT.; Lee, VK.; Hill, CE.; Cheuk, W.; Toh, HC.; Kesavan, S.; Chan, EW.; Weiss, SW. (Jan 2006). "Epstein-Barr virus-associated smooth muscle tumors are distinctive mesenchymal tumors reflecting multiple infection events: a clinicopathologic and molecular analysis of 29 tumors from 19 patients.". Am J Surg Pathol 30 (1): 75-82. PMID 16330945.