Difference between revisions of "Epstein-Barr virus-associated smooth muscle tumour"

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'''[[Epstein-Barr virus]]-associated smooth muscle tumour''' is a very uncommon [[soft tissue lesion]].<ref name=pmid16330945>{{Cite journal  | last1 = Deyrup | first1 = AT. | last2 = Lee | first2 = VK. | last3 = Hill | first3 = CE. | last4 = Cheuk | first4 = W. | last5 = Toh | first5 = HC. | last6 = Kesavan | first6 = S. | last7 = Chan | first7 = EW. | last8 = Weiss | first8 = SW. | title = Epstein-Barr virus-associated smooth muscle tumors are distinctive mesenchymal tumors reflecting multiple infection events: a clinicopathologic and molecular analysis of 29 tumors from 19 patients. | journal = Am J Surg Pathol | volume = 30 | issue = 1 | pages = 75-82 | month = Jan | year = 2006 | doi =  | PMID = 16330945 }}</ref>
'''[[Epstein-Barr virus]]-associated smooth muscle tumour''' is a very uncommon [[soft tissue lesions|soft tissue lesion]].<ref name=pmid16330945>{{Cite journal  | last1 = Deyrup | first1 = AT. | last2 = Lee | first2 = VK. | last3 = Hill | first3 = CE. | last4 = Cheuk | first4 = W. | last5 = Toh | first5 = HC. | last6 = Kesavan | first6 = S. | last7 = Chan | first7 = EW. | last8 = Weiss | first8 = SW. | title = Epstein-Barr virus-associated smooth muscle tumors are distinctive mesenchymal tumors reflecting multiple infection events: a clinicopathologic and molecular analysis of 29 tumors from 19 patients. | journal = Am J Surg Pathol | volume = 30 | issue = 1 | pages = 75-82 | month = Jan | year = 2006 | doi =  | PMID = 16330945 }}</ref>


==General==
*Immunosuppressed individuals.
*Caused by [[Epstein-Barr virus]].
==Microscopic==
Features:
*Spindle cell lesion.
DDx:
*[[Gastrointestinal stromal tumour]].
*[[Leiomyosarcoma]].
==IHC==
*SMA +ve
*Desmin +ve/-ve.
*CD34 -ve.
*CD117 -ve.


==References==
==References==

Revision as of 02:05, 4 March 2013

Epstein-Barr virus-associated smooth muscle tumour is a very uncommon soft tissue lesion.[1]

General

Microscopic

Features:

  • Spindle cell lesion.

DDx:

IHC

  • SMA +ve
  • Desmin +ve/-ve.
  • CD34 -ve.
  • CD117 -ve.

References

  1. ↑ Deyrup, AT.; Lee, VK.; Hill, CE.; Cheuk, W.; Toh, HC.; Kesavan, S.; Chan, EW.; Weiss, SW. (Jan 2006). "Epstein-Barr virus-associated smooth muscle tumors are distinctive mesenchymal tumors reflecting multiple infection events: a clinicopathologic and molecular analysis of 29 tumors from 19 patients.". Am J Surg Pathol 30 (1): 75-82. PMID 16330945.
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