Difference between revisions of "Hypertension"
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====Microscopic==== | ====Microscopic==== | ||
Features:<ref name=pmid16450803>{{cite journal |author=Auer RN, Sutherland GR |title=Primary intracerebral hemorrhage: pathophysiology |journal=Can J Neurol Sci |volume=32 Suppl 2 |issue= |pages=S3–12 |year=2005 |month=December |pmid=16450803 |doi= |url=}}</ref> | Features:<ref name=pmid16450803>{{cite journal |author=Auer RN, Sutherland GR |title=Primary intracerebral hemorrhage: pathophysiology |journal=Can J Neurol Sci |volume=32 Suppl 2 |issue= |pages=S3–12 |year=2005 |month=December |pmid=16450803 |doi= |url=}}</ref> | ||
*Small aneurysms with a fusiform shape. | *Small aneurysms (~300 micrometers) with a fusiform shape. | ||
*Vessel wall changes: | *Vessel wall changes: | ||
**Early: | **Early: | ||
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***Apoptotic smooth muscle cell death and collagen deposition. | ***Apoptotic smooth muscle cell death and collagen deposition. | ||
Image: [http://missinglink.ucsf.edu/lm/introductionneuropathology/Response%20_to_Injury/Injury_Images/hypertension1w.jpg C-B aneurysm (ucsf.edu)]. | |||
==Eye== | ==Eye== | ||
*Blindness. | *Blindness. | ||
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==References== | ==References== | ||
{{reflist| | {{reflist|1}} | ||
==External links== | |||
*[http://missinglink.ucsf.edu/lm/introductionneuropathology/Response%20_to_Injury/Microvascular.html Microvascular disease (ucsf.edu)]. | |||
[[Category:Cardiovascular pathology]] | [[Category:Cardiovascular pathology]] | ||
Revision as of 12:24, 23 September 2010
Hypertension is very common and affects multiple organs. Clinically, it is usually classified as primary (idiopathic) and secondary.
Brain
Charcôt-Bouchard aneurysms
General
- AKA miliary aneurysms.
- Intracerebral hemorrhages.
Microscopic
Features:[1]
- Small aneurysms (~300 micrometers) with a fusiform shape.
- Vessel wall changes:
- Early:
- Proliferation of arteriolar smooth muscle
- Late:
- Apoptotic smooth muscle cell death and collagen deposition.
- Early:
Image: C-B aneurysm (ucsf.edu).
Eye
- Blindness.
Heart
- Concentric hypertrophy.
Kidney
- Renal failure.