Difference between revisions of "Osteoarthritis"
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*Subchondral cysts. | *Subchondral cysts. | ||
*+/-Mild inflammation (lymphocytes). | *+/-Mild inflammation (lymphocytes). | ||
*Villous hyperplasia - synovium has finger-like projections into the joint space. | *+/-Villous hyperplasia - synovium has finger-like projections into the joint space. | ||
**Normal synovium has a flat surface. | **Normal synovium has a flat surface. | ||
Image: | Image: | ||
*[http://ars.els-cdn.com/content/image/1-s2.0-S8756328212000683-gr1.jpg Osteoarthritis - panel B (els-cdn.com)]. | *[http://ars.els-cdn.com/content/image/1-s2.0-S8756328212000683-gr1.jpg Osteoarthritis showing villous hyperplasia - panel B (els-cdn.com)]. | ||
==See also== | ==See also== | ||
Revision as of 12:39, 9 October 2012
Osteoarthritis, abbreviated OA, is a degenerative disease of the joint.
General
Risks
It is associated with:[1]
- Advanced age.
- Trauma.
- Unusual loading (bony misalignment, obesity).
Gross pathology/radiology
Features:[2]
- Loss of cartilage, especially asymmetrical (eburnation).
- Osteophyte formation.
- Subchondral cysts.
- Subchondral sclerosis.
Memory device LOSS: Loss of cartilage, Osteophyte formation, Subchondral cysts, Subchondral sclerosis.
Microscopic
Features:[3]
- Vertical clefts of the cartilage - characteristic.
- Thickening of bony trabeculae (reactive phenomenon) due to fibrosis.
- Subchondral cysts.
- +/-Mild inflammation (lymphocytes).
- +/-Villous hyperplasia - synovium has finger-like projections into the joint space.
- Normal synovium has a flat surface.
Image:
See also
References
- ↑ Martel-Pelletier, J.; Pelletier, JP. (Apr 2010). "Is osteoarthritis a disease involving only cartilage or other articular tissues?". Eklem Hastalik Cerrahisi 21 (1): 2-14. PMID 20302555. http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.tevak.org-images-Eklemlinkout.png.
- ↑ Swagerty, DL.; Hellinger, D. (Jul 2001). "Radiographic assessment of osteoarthritis.". Am Fam Physician 64 (2): 279-86. PMID 11476273. http://www.aafp.org/afp/2001/0715/p279.html.
- ↑ Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 658. ISBN 978-0781765275.
