Difference between revisions of "Oncogene"
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''' | An '''oncogene''' is a [[cancer]] gene, derived from a '''proto-oncogene'''. | ||
Examples | ==Examples== | ||
*EGFR<ref name=omim131550>{{OMIM|131550}}</ref> - [[lung adenocarcinoma]]. | *EGFR<ref name=omim131550>{{OMIM|131550}}</ref> - [[lung adenocarcinoma]]. | ||
*PDGFB<ref name=omim190040>{{OMIM|190040}}</ref> - [[dermatofibrosarcoma protuberans]]. | *PDGFB<ref name=omim190040>{{OMIM|190040}}</ref> - [[dermatofibrosarcoma protuberans]]. | ||
*BRAF | *BRAF<ref name=omim164757>{{OMIM|164757}}</ref> - [[papillary thyroid carcinoma tall cell variant]]. | ||
*KRAS | *KRAS<ref name=omim190070>{{OMIM|190070}}</ref> - [[invasive ductal carcinoma of the pancreas]]. | ||
*MYC<ref name=omim190080>{{OMIM|190080}}</ref> - [[Burkitt lymphoma]]. | *MYC<ref name=omim190080>{{OMIM|190080}}</ref> - [[Burkitt lymphoma]]. | ||
*MET<ref name=omim164860>{{OMIM|164860}}</ref> - [[papillary renal cell carcinoma]]. | *MET<ref name=omim164860>{{OMIM|164860}}</ref> - [[papillary renal cell carcinoma]]. |
Revision as of 13:26, 4 May 2012
An oncogene is a cancer gene, derived from a proto-oncogene.
Examples
- EGFR[1] - lung adenocarcinoma.
- PDGFB[2] - dermatofibrosarcoma protuberans.
- BRAF[3] - papillary thyroid carcinoma tall cell variant.
- KRAS[4] - invasive ductal carcinoma of the pancreas.
- MYC[5] - Burkitt lymphoma.
- MET[6] - papillary renal cell carcinoma.
See also
References
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 131550
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 190040
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 164757
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 190070
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 190080
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 164860