Difference between revisions of "Vascular disease"
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===Microscopic=== | ===Microscopic=== | ||
Features:<ref>URL: [http://emedicine.medscape.com/article/756835-overview http://emedicine.medscape.com/article/756835-overview]. Accessed on: 12 August 2010.</ref><ref name=pmid17620463>{{cite journal |author=Ha HI, Seo JB, Lee SH, ''et al.'' |title=Imaging of Marfan syndrome: multisystemic manifestations |journal=Radiographics |volume=27 |issue=4 |pages=989–1004 |year=2007 |pmid=17620463 |doi=10.1148/rg.274065171 |url=http://radiographics.rsna.org/content/27/4/989.full}}</ref> | Features:<ref>URL: [http://emedicine.medscape.com/article/756835-overview http://emedicine.medscape.com/article/756835-overview]. Accessed on: 12 August 2010.</ref><ref name=pmid17620463>{{cite journal |author=Ha HI, Seo JB, Lee SH, ''et al.'' |title=Imaging of Marfan syndrome: multisystemic manifestations |journal=Radiographics |volume=27 |issue=4 |pages=989–1004 |year=2007 |pmid=17620463 |doi=10.1148/rg.274065171 |url=http://radiographics.rsna.org/content/27/4/989.full}}</ref> | ||
*Basophilic ground substance in the media ( | *Basophilic ground substance in the media (seen on Movat's [[stain]]). | ||
*Disruption of the elastic lamina (seen on elastic trichrome stain). | *Disruption of the elastic lamina (seen on elastic trichrome stain). | ||
*+/-Focal necrosis. | *+/-Focal necrosis. | ||
Revision as of 12:52, 25 August 2010
The article covers vascular disease. Vasculitides are covered in a separate article called vasculitides.
Great vessels
When things go wrong here, you see a cardiac surgeon.
Aortic dissection
Associations
Heritable:[1]
- Marfan's syndrome.
- Loeys-Dietz syndrome.[2]
- Marfan-like syndrome.
- Ehlers-Danlos syndrome.
- Bicuspid aortic valve.
Others:
- Tertiary syphilis.
Cystic medial degeneration
General
Microscopic
- Basophilic ground substance in the media (seen on Movat's stain).
- Disruption of the elastic lamina (seen on elastic trichrome stain).
- +/-Focal necrosis.
Images: Marfan's syndrome (radiographics.rsna.org).
See also
References
- ↑ Gleason TG (2005). "Heritable disorders predisposing to aortic dissection". Semin. Thorac. Cardiovasc. Surg. 17 (3): 274-81. doi:10.1053/j.semtcvs.2005.06.001. PMID 16253833.
- ↑ Loeys BL, Schwarze U, Holm T, et al (August 2006). "Aneurysm syndromes caused by mutations in the TGF-beta receptor". N. Engl. J. Med. 355 (8): 788-98. doi:10.1056/NEJMoa055695. PMID 16928994. http://content.nejm.org/cgi/content/full/355/8/788.
- ↑ URL: http://emedicine.medscape.com/article/756835-overview. Accessed on: 12 August 2010.
- ↑ URL: http://emedicine.medscape.com/article/756835-overview. Accessed on: 12 August 2010.
- ↑ Ha HI, Seo JB, Lee SH, et al. (2007). "Imaging of Marfan syndrome: multisystemic manifestations". Radiographics 27 (4): 989–1004. doi:10.1148/rg.274065171. PMID 17620463. http://radiographics.rsna.org/content/27/4/989.full.