Difference between revisions of "Surgical margins"
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'''Surgical margins''', often simply referred to as '''margins''', are the set of surfaces that were cut by the surgeon in order to remove the specimen from the body. They are important as an incompletely removed disease process may lead to re-occurrence. | '''Surgical margins''', often simply referred to as '''margins''', are the set of surfaces that were cut by the surgeon in order to remove the specimen from the body. They are important as an incompletely removed disease process may lead to re-occurrence. | ||
Most often, positive margins, i.e. surgical margins with disease present, suck. For example, in locally advanced [[rectal cancer]], in one study,<ref name=pmid17614249>{{cite journal |author=Larsen SG, Wiig JN, Dueland S, Giercksky KE |title=Prognostic factors after preoperative irradiation and surgery for locally advanced rectal cancer |journal=Eur J Surg Oncol |volume=34 |issue=4 |pages=410–7 |year=2008 |month=April |pmid=17614249 |doi=10.1016/j.ejso.2007.05.012 |url=}}</ref> five year survival was found to be 60%, 31% and 0% for R0 (no tumour at the margin), R1 (microscopic tumour at the margin), and R2 (macroscopic tumour at the margin) resections respectively. | |||
==Types of margins== | ==Types of margins== | ||
| Line 11: | Line 13: | ||
==See also== | ==See also== | ||
*[[Basics]]. | *[[Basics]]. | ||
==References== | |||
{{Reflist|1}} | |||
[[Category:Basics]] | [[Category:Basics]] | ||
Revision as of 13:52, 6 April 2012
Surgical margins, often simply referred to as margins, are the set of surfaces that were cut by the surgeon in order to remove the specimen from the body. They are important as an incompletely removed disease process may lead to re-occurrence.
Most often, positive margins, i.e. surgical margins with disease present, suck. For example, in locally advanced rectal cancer, in one study,[1] five year survival was found to be 60%, 31% and 0% for R0 (no tumour at the margin), R1 (microscopic tumour at the margin), and R2 (macroscopic tumour at the margin) resections respectively.
Types of margins
- En face.
- Sample the complete surface.
- No information about the distance between the margin and lesion can be obtained.
- On edge, AKA perpendicular margin.
- Sample a subset of the surface.
- The distance between the margin and lesion can be measured.
See also
References
- ↑ Larsen SG, Wiig JN, Dueland S, Giercksky KE (April 2008). "Prognostic factors after preoperative irradiation and surgery for locally advanced rectal cancer". Eur J Surg Oncol 34 (4): 410–7. doi:10.1016/j.ejso.2007.05.012. PMID 17614249.