Difference between revisions of "Products of conception"
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'''Products of conception''', abbreviated '''POC''', is stuff formed from the union of egg and sperm. | '''Products of conception''', abbreviated '''POC''', is stuff formed from the union of egg and sperm. This article covers POC superficially. | ||
There are separate articles for ''[[chorionic villi]]'' and ''[[gestational trophoblastic disease]]''. | |||
==History== | ==History== | ||
*Therapeutic abortions - may be abbreviated "MVC" (manual vacuum aspiration)<ref>{{cite journal |author=Edelman A, Nichols MD, Jensen J |title=Comparison of pain and time of procedures with two first-trimester abortion techniques performed by residents and faculty |journal=Am. J. Obstet. Gynecol. |volume=184 |issue=7 |pages=1564-7 |year=2001 |month=June |pmid=11408881 |doi= |url=http://linkinghub.elsevier.com/retrieve/pii/S0002937801372241}}</ref> | *Therapeutic abortions - may be abbreviated "MVC" (manual vacuum aspiration).<ref>{{cite journal |author=Edelman A, Nichols MD, Jensen J |title=Comparison of pain and time of procedures with two first-trimester abortion techniques performed by residents and faculty |journal=Am. J. Obstet. Gynecol. |volume=184 |issue=7 |pages=1564-7 |year=2001 |month=June |pmid=11408881 |doi= |url=http://linkinghub.elsevier.com/retrieve/pii/S0002937801372241}}</ref> | ||
==Microscopic== | ==Microscopic== | ||
| Line 44: | Line 46: | ||
==Diagnostic tests== | ==Diagnostic tests== | ||
*Chorionic villus sampling (10-12 weeks???) | *Chorionic villus sampling (10-12 weeks???). | ||
*Amniocentesis (15-16 weeks+) | *Amniocentesis (15-16 weeks+). | ||
==See also== | |||
*[[Gynecologic pathology]]. | |||
*[[Chorionic villi]]. | |||
*[[Gestational trophoblastic disease]]. | |||
==References== | ==References== | ||
Revision as of 17:01, 17 August 2010
Products of conception, abbreviated POC, is stuff formed from the union of egg and sperm. This article covers POC superficially.
There are separate articles for chorionic villi and gestational trophoblastic disease.
History
- Therapeutic abortions - may be abbreviated "MVC" (manual vacuum aspiration).[1]
Microscopic
Features:
- Chorionic villi are need to call POC - key feature.
- Cytotrophoblast.
- Centre of villi often have fetal red blood cells (which have nuclei) -- not required for diagnosis of POC.
- Should have decidual reaction of endometrium.
- Decidual changes -- mnemonic NEW:
- Nucleus central.
- Eosinophilic cytoplasm.
- Well-defined cell borders.
- Decidual changes -- mnemonic NEW:
- Embryo or fetus - a bonus.
ASIDE:
- Embryo = conceptus before 8 weeks.
- Fetus = conceptus 8th weeks 'til birth.
Beta-hCG
Calculator: http://www.countdowntopregnancy.com/tools/beta_doubling_calculator.php
Ectopic pregnancy
- Chorionic villi have to be identified (in some location, e.g. Fallopian tube) to Dx a pregnancy.
- Endometrium: decidual reaction, as seen in any pregnancy.
Arias-Stellas reaction
- Large nuclei - to the novice... it looks really scary.
- NC ratio is preserved.
- May see nuclear clearing.[2]
Screening tests
First trimester screen
- PAPP-A.
- Nuchal translucency.
- beta-hCG.
Maternal serum screen
- Alpha-fetoprotein.
- Beta-hCG.
- Estriol.
Diagnostic tests
- Chorionic villus sampling (10-12 weeks???).
- Amniocentesis (15-16 weeks+).
See also
References
- ↑ Edelman A, Nichols MD, Jensen J (June 2001). "Comparison of pain and time of procedures with two first-trimester abortion techniques performed by residents and faculty". Am. J. Obstet. Gynecol. 184 (7): 1564-7. PMID 11408881. http://linkinghub.elsevier.com/retrieve/pii/S0002937801372241.
- ↑ Tadrous, Paul.J. Diagnostic Criteria Handbook in Histopathology: A Surgical Pathology Vade Mecum (1st ed.). Wiley. pp. 236 (bottom). ISBN 978-0470519035. .