Difference between revisions of "Small cell carcinoma"

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m (→‎Special types: +ovarian)
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=Special types=
=Special types=
==Ovarian small cell carcinoma of the hypercalcemic type==
*[[Ovarian small cell carcinoma of the hypercalcemic type]].
*[[AKA]] ''small cell carcinoma, hypercalcemic type'', [[AKA]] ''small cell carcinoma of the ovary, hypercalcemic type''.
===General===
*Hypercalcemia.<ref name=pmid7943531>{{Cite journal  | last1 = Young | first1 = RH. | last2 = Oliva | first2 = E. | last3 = Scully | first3 = RE. | title = Small cell carcinoma of the ovary, hypercalcemic type. A clinicopathological analysis of 150 cases. | journal = Am J Surg Pathol | volume = 18 | issue = 11 | pages = 1102-16 | month = Nov | year = 1994 | doi =  | PMID = 7943531 }}</ref>
*Rare.
 
===Microscopic===
Features:<ref name=pmid7943531/>
*Small cell carcinoma.
*Follicle-like spaces.
 
Images:
*[http://webpathology.com/image.asp?n=6&Case=531 OSSCHT - low mag. (webpathology.com)].
*[http://webpathology.com/image.asp?case=531&n=5 OSSCHT - high mag. (webpathology.com)].


=See also=
=See also=

Revision as of 00:33, 13 December 2011

Small cell carcinoma is a type of carcinoma. It is mostly commonly from the lung ~95% of cases.[1]

Overview

Grouping

May be grouped as:[1]

Sites other than lung

General

Classic tumour with paraneoplastic syndromes - may be associated with:[4]

  • Syndrome of inappropriate antidiuretic hormone secretion (SIADH).
    • Clinical: hyponatremia.
  • Paraneoplastic cerebellar degeneration.
  • Lambert-Eaton myasthenic syndrome.

Microscopic

Features:

  • Small cells -- typically 15-20 micrometers ~ 2x the size of RBC.
  • Scant cytoplasm.
  • Stippled chromatin.
  • +/-Nuclear moulding.

Images:

DDx:

Special types

See also

References

  1. ↑ 1.0 1.1 Grossman, RA.; Pedroso, FE.; Byrne, MM.; Koniaris, LG.; Misra, S. (May 2011). "Does surgery or radiation therapy impact survival for patients with extrapulmonary small cell cancers?". J Surg Oncol. doi:10.1002/jso.21976. PMID 21618245.
  2. ↑ Cesaretti, M.; Guarnieri, A.; Gaggelli, I.; Tirone, A.; Francioli, N.; Carli, AF.. "Small cell carcinoma of the breast. Report of a case.". Ann Ital Chir 82 (1): 61-4. PMID 21657157.
  3. ↑ Beach, DF.; Klump, WJ.; Haddad, G.; Reid, LM.; Schwarting, R.; Hageboutros, A. (Jun 2011). "Extrapulmonary small cell: a novel case of small cell carcinoma of the thyroid gland.". Med Oncol. doi:10.1007/s12032-011-9996-7. PMID 21644012.
  4. ↑ Sher, T.; Dy, GK.; Adjei, AA. (Mar 2008). "Small cell lung cancer.". Mayo Clin Proc 83 (3): 355-67. PMID 18316005.
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