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Difference between revisions of "Scleroderma"
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Clinical: | Clinical: | ||
*Anti-centromere antibody (ACA) +ve. | *Anti-centromere antibody (ACA) +ve. | ||
**Common in ''limited systemic scleroderma'', [[AKA]] CREST | **Common in ''limited systemic scleroderma'', [[AKA]] CREST syndrome. | ||
*Scl-70 (topoisomerase I) +ve. | *Scl-70 (topoisomerase I) +ve. | ||
**Common in ''diffuse scleroderma''. | **Common in ''diffuse scleroderma''. | ||
CREST syndrome: | |||
*Calcinosis. | |||
*Raynaud's phenomenon. | |||
*[[esophagus|Esophageal]] dysmotility. | |||
*Sclerodactyly. | |||
*Telangiectasia. | |||
==Associated pathology== | ==Associated pathology== | ||