Difference between revisions of "Scleroderma"

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==General==
==General==
Clinical:
Clinical:
*Anti-centromere antibody +ve.
*Anti-centromere antibody (ACA) +ve.
**Common in ''limited systemic scleroderma'', [[AKA]] CREST Syndrome.
**Common in ''limited systemic scleroderma'', [[AKA]] CREST Syndrome.
*Scl-70 (topoisomerase I).
*Scl-70 (topoisomerase I) +ve.
**Common in ''diffuse scleroderma''.
**Common in ''diffuse scleroderma''.



Revision as of 22:44, 3 December 2011

Scleroderma is a disease that keeps rheumatologists busy.

General

Clinical:

  • Anti-centromere antibody (ACA) +ve.
    • Common in limited systemic scleroderma, AKA CREST Syndrome.
  • Scl-70 (topoisomerase I) +ve.
    • Common in diffuse scleroderma.

Associated pathology

See also