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Difference between revisions of "Embryonal tumour with multilayered rosettes"
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Embryonal tumour with multilayered rosettes (view source)
Revision as of 11:45, 4 October 2017
, 11:45, 4 October 2017IHC
Jensflorian (talk | contribs) (ETMR subsetzs) |
Jensflorian (talk | contribs) (IHC) |
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==IHC== | ==IHC== | ||
*LIN28+ve. | *LIN28+ve. | ||
**Note: Some AT/RT may be focally +ve. <ref>{{Cite journal | last1 = Rao | first1 = S. | last2 = Rajeswarie | first2 = RT. | last3 = Chickabasaviah Yasha | first3 = T. | last4 = Nandeesh | first4 = BN. | last5 = Arivazhagan | first5 = A. | last6 = Santosh | first6 = V. | title = LIN28A, a sensitive immunohistochemical marker for Embryonal Tumor with Multilayered Rosettes (ETMR), is also positive in a subset of Atypical Teratoid/Rhabdoid Tumor (AT/RT). | journal = Childs Nerv Syst | volume = | issue = | pages = | month = Jul | year = 2017 | doi = 10.1007/s00381-017-3551-6 | PMID = 28744687 }}</ref> | |||
*CD99: focally +ve. | |||
*Synaptophysin: Neuropil-like areas +ve. | |||
*GFAP: usu -ve. | |||
*INI1 +ve. | |||
*Mib1: 20-80%. | |||
<gallery>File:LIN28 ependymoblastoma.jpg| LIN28 positive ETMR.</gallery> | <gallery>File:LIN28 ependymoblastoma.jpg| LIN28 positive ETMR.</gallery> | ||