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→Other neuroepithelial tumours: CRINET
Jensflorian (talk | contribs) (→Location (most common): update) |
Jensflorian (talk | contribs) (→Other neuroepithelial tumours: CRINET) |
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==Other neuroepithelial tumours== | ==Other neuroepithelial tumours== | ||
* Astroblastoma | * [[Neuropathology_tumours#Astroblastoma|Astroblastoma]]. | ||
* Chordoid glioma of the third ventricle | * [[Neuropathology_tumours#Chordoid glioma of the third ventricl|Chordoid glioma of the third ventricle]]. | ||
* [[Angiocentric glioma]] | * [[Angiocentric glioma]]. | ||
* [[Neuropathology_tumours#Cribifiorm_neuroepithelial_tumour|Cribifiorm neuroepithelial tumour]]. | |||
===Astroblastoma=== | ===Astroblastoma=== | ||
*No WHO grade yet. | *No WHO grade yet.<ref>{{Ref:WHOCNS|88}}</ref> | ||
*Very rare superficial tumor of young age. | *Very rare superficial tumor of young age.<ref>{{Cite journal | last1 = Narayan | first1 = S. | last2 = Kapoor | first2 = A. | last3 = Singhal | first3 = MK. | last4 = Jakhar | first4 = SL. | last5 = Bagri | first5 = PK. | last6 = Rajput | first6 = PS. | last7 = Kumar | first7 = HS. | title = Astroblastoma of cerebrum: A rare case report and review of literature. | journal = J Cancer Res Ther | volume = 11 | issue = 3 | pages = 667 | month = | year = | doi = 10.4103/0973-1482.140800 | PMID = 26458709 }}</ref> | ||
*Large, cystic. Pushing margin towards CNS. | *Large, cystic. Pushing margin towards CNS. | ||
*Vasocentric growth, plump cells with absence of fibrillary pattern. | *Vasocentric growth, plump cells with absence of fibrillary pattern. | ||
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* Few mitoses. | * Few mitoses. | ||
* GFAP+ve, MIB-1 1-3%. | * GFAP+ve, MIB-1 1-3%. | ||
===Cribifiorm neuroepithelial tumour=== | |||
AKA: '''CRINET'''. | |||
*Not listed in the current WHO classification. | |||
*First description in 2009.<ref>{{Cite journal | last1 = Hasselblatt | first1 = M. | last2 = Oyen | first2 = F. | last3 = Gesk | first3 = S. | last4 = Kordes | first4 = U. | last5 = Wrede | first5 = B. | last6 = Bergmann | first6 = M. | last7 = Schmid | first7 = H. | last8 = Frühwald | first8 = MC. | last9 = Schneppenheim | first9 = R. | title = Cribriform neuroepithelial tumor (CRINET): a nonrhabdoid ventricular tumor with INI1 loss and relatively favorable prognosis. | journal = J Neuropathol Exp Neurol | volume = 68 | issue = 12 | pages = 1249-55 | month = Dec | year = 2009 | doi = 10.1097/NEN.0b013e3181c06a51 | PMID = 19915490 }}</ref> | |||
*Around ventricles.<ref>{{Cite journal | last1 = Arnold | first1 = MA. | last2 = Stallings-Archer | first2 = K. | last3 = Marlin | first3 = E. | last4 = Grondin | first4 = R. | last5 = Olshefski | first5 = R. | last6 = Biegel | first6 = JA. | last7 = Pierson | first7 = CR. | title = Cribriform neuroepithelial tumor arising in the lateral ventricle. | journal = Pediatr Dev Pathol | volume = 16 | issue = 4 | pages = 301-7 | month = | year = | doi = 10.2350/12-12-1287-CR.1 | PMID = 23495723 }}</ref> | |||
*Young children.<ref>{{Cite journal | last1 = Park | first1 = JY. | last2 = Kim | first2 = E. | last3 = Kim | first3 = DW. | last4 = Chang | first4 = HW. | last5 = Kim | first5 = SP. | title = Cribriform neuroepithelial tumor in the third ventricle: a case report and literature review. | journal = Neuropathology | volume = 32 | issue = 5 | pages = 570-6 | month = Oct | year = 2012 | doi = 10.1111/j.1440-1789.2011.01293.x | PMID = 22239490 }}</ref> | |||
*Small undifferentiated cells arranged in cribriform strands and trabeculae of varying thickness. | |||
*MAP2+ve, Synaptophysin+ve, CK+/-ve. MIB-1: 30%. | |||
*INI-1 loss, but no rhabdoid features and good prognosis. | |||
*Stable genomic profile.<ref>{{Cite journal | last1 = Gessi | first1 = M. | last2 = Japp | first2 = AS. | last3 = Dreschmann | first3 = V. | last4 = Zur Mühlen | first4 = A. | last5 = Goschzik | first5 = T. | last6 = Dörner | first6 = E. | last7 = Pietsch | first7 = T. | title = High-Resolution Genomic Analysis of Cribriform Neuroepithelial Tumors of the Central Nervous System. | journal = J Neuropathol Exp Neurol | volume = 74 | issue = 10 | pages = 970-4 | month = Oct | year = 2015 | doi = 10.1097/NEN.0000000000000239 | PMID = 26352987 }}</ref> | |||
==Neuronal and mixed neuronal/glial tumours== | ==Neuronal and mixed neuronal/glial tumours== | ||