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Difference between revisions of "Eccrine spiradenoma"
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→Microscopic
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Features:<ref name=dermatlas>URL: [http://www.dermatlas.com/derm/IndexDisplay.cfm?ImageID=-1193575448 http://www.dermatlas.com/derm/IndexDisplay.cfm?ImageID=-1193575448]. Accessed on: 29 November 2010.</ref><ref>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970191-7 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970191-7]. Accessed on: 10 May 2011.</ref> | Features:<ref name=dermatlas>URL: [http://www.dermatlas.com/derm/IndexDisplay.cfm?ImageID=-1193575448 http://www.dermatlas.com/derm/IndexDisplay.cfm?ImageID=-1193575448]. Accessed on: 29 November 2010.</ref><ref>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970191-7 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970191-7]. Accessed on: 10 May 2011.</ref> | ||
*Dense nests of cells in the dermis; "dermal blue balls". | *Dense nests of cells in the dermis; "dermal blue balls". | ||
* | *Biphasic cell population: | ||
** | **outer dark cells with small hyperchromatic nuclei and minimal cytoplasm. | ||
** | **inner larger cells with vesicular nuclei and more cytoplasm. | ||
**In some areas the two cell types mix together with dispersed hyaline droplets. | |||
*Ductal differentiation. | |||
*These cells form lobules that are surrounded by hyaline or reticulin sheath or. | |||
*+/-Lymphocytes. | *+/-Lymphocytes. | ||
*Vascular component - large and small blood vessels. | *Vascular component - large and small blood vessels. | ||
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DDx: | DDx: | ||
*[[Dermal cylindroma]]- | *[[Dermal cylindroma]]- | ||
**These two tumors are very closely related | **These two tumors are very closely related and overlap. | ||
**Many tumors have areas of both spiradenoma and cylindroma. | **Many tumors have areas of both spiradenoma and cylindroma. | ||
**The lobules of cylindroma are more consistently discrete and surrounded by prominent hyaline material. | |||
**Individual lobules of cylindroma fit together like pieces of a puzzle. | |||
*[[Trichoepithelioma]]. | *[[Trichoepithelioma]]. | ||
*[[Glomus tumour]]. | *[[Glomus tumour]], hemangioma or hemangiopericytoma (vascular spiradenomas). | ||
**The location | **The location often speaks against glomus tumour. | ||
*Lymphoid aggregate (spiradenoma will be cytokeratin positive) | |||
===Images=== | ===Images=== | ||