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Difference between revisions of "Brain metastasis"
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| Micro = usu. well-demarcated border between brain and lesion, no cytoplasmic processes (seen in glial tumours), usu. have [[nuclear atypia]] of malignancy, +/-glandular architecture, +/-nucleoli seen | | Micro = usu. well-demarcated border between brain and lesion, no cytoplasmic processes (seen in glial tumours), usu. have [[nuclear atypia]] of malignancy, +/-glandular architecture, +/-nucleoli seen | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = primary brain tumour | | LMDDx = primary brain tumour - see ''[[primary brain tumour versus secondary brain tumour]]'' | ||
| Stains = | | Stains = | ||
| IHC = GFAP -ve, dependent on primary - typical +ve for keratins | | IHC = GFAP -ve, dependent on primary - typical +ve for keratins (as carcinoma) | ||
| EM = | | EM = | ||
| Molecular = | | Molecular = | ||
| Line 21: | Line 21: | ||
| Signs = | | Signs = | ||
| Symptoms = | | Symptoms = | ||
| Prevalence = | | Prevalence = most common brain tumour (adults) | ||
| Bloodwork = | | Bloodwork = | ||
| Rads = intra-axial, typically | | Rads = intra-axial, typically grey-white junction, cerebellum (esp. in adults) | ||
| Endoscopy = | | Endoscopy = | ||
| Prognosis = poor | | Prognosis = poor | ||