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Difference between revisions of "Clear cell carcinoma of the ovary"
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Clear cell carcinoma of the ovary (view source)
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'''Clear cell carcinoma of the ovary''', also '''ovarian clear cell carcinoma''' (abbreviated '''OCCC''', is an aggressive [[malignant]] [[ovarian tumours|tumour of the ovary]]. | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | |||
| Image = Ovarian clear cell carcinoma - very high mag.jpg | |||
| Width = | |||
| Caption = Ovarian clear cell carcinoma. [[H&E stain]]. | |||
| Synonyms = ovarian clear cell carcinoma, ovarian clear cell adenocarcinoma, clear cell adenocarcinoma of the ovary | |||
| Micro = cystic/tubular architecture (may be papillary and/or solid), clear cytoplasm (may be sparse), [[hobnail morphology]] - apical surface larger than basal surface ("nuclei bulge into the lumen"), +/-hyaline droplets, prominent [[nucleoli]] | |||
| Subtypes = | |||
| LMDDx = [[serous carcinoma of the ovary]], other [[serous carcinoma]]s, other [[clear cell tumours]] (e.g. [[clear cell renal cell carcinoma]]), [[Arias-Stella reaction]] within [[endometriosis]] | |||
| Stains = | |||
| IHC = HNF-1beta +ve, WT-1 -ve, CK7 +ve, CD10 -ve, CK20 -ve | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = mass, yellow colour, usu. unilateral | |||
| Grossing = | |||
| Site = [[ovary]] - see ''[[ovarian tumours]]'' | |||
| Assdx = [[endometriosis]], [[pulmonary embolism]] | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = poor | |||
| Other = | |||
| ClinDDx = other [[ovarian tumours]], other pelvic and abdominal tumours | |||
| Tx = | |||
}} | |||
'''Clear cell carcinoma of the ovary''', also '''ovarian clear cell carcinoma''' (abbreviated '''OCCC'''), is an aggressive [[malignant]] [[ovarian tumours|tumour of the ovary]]. | |||
It often forms glands; thus, it is also known as '''ovarian clear cell [[adenocarcinoma]]''', and '''clear cell adenocarcinoma of the ovary'''. | It often forms glands; thus, it is also known as '''ovarian clear cell [[adenocarcinoma]]''', and '''clear cell adenocarcinoma of the ovary'''. | ||