Difference between revisions of "Follicular lymphoma"

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965 bytes added ,  23:28, 29 December 2013
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| Rads      =
| Rads      =
| Endoscopy  =
| Endoscopy  =
| Prognosis  = usually good
| Prognosis  = moderate to good
| Other      =
| Other      =
| ClinDDx    = other causes of lymphadenopathy - other [[lymphoma]]s, metastatic carcinoma
| ClinDDx    = other causes of lymphadenopathy - other [[lymphoma]]s, metastatic carcinoma
| Tx        =
| Tx        =
}}
}}
'''Follicular lymphoma''', abbreviated '''FL''', is a very common [[non-Hodgkin lymphoma]].  It is a [[small cell lymphoma]] and usually has an indolent behaviour.
'''Follicular lymphoma''', abbreviated '''FL''', is a very common [[non-Hodgkin lymphoma]].  It is a [[small cell lymphoma]].


==General==
==General==
*A very common type of lymphoma.
*A very common type of lymphoma.
*Usually an indolent course.
*Moderate prognosis - overall five year survival ~ 66% in one cohort without transformation.<ref name=pmid23897955>{{Cite journal  | last1 = Link | first1 = BK. | last2 = Maurer | first2 = MJ. | last3 = Nowakowski | first3 = GS. | last4 = Ansell | first4 = SM. | last5 = Macon | first5 = WR. | last6 = Syrbu | first6 = SI. | last7 = Slager | first7 = SL. | last8 = Thompson | first8 = CA. | last9 = Inwards | first9 = DJ. | title = Rates and outcomes of follicular lymphoma transformation in the immunochemotherapy era: a report from the University of Iowa/MayoClinic Specialized Program of Research Excellence Molecular Epidemiology Resource. | journal = J Clin Oncol | volume = 31 | issue = 26 | pages = 3272-8 | month = Sep | year = 2013 | doi = 10.1200/JCO.2012.48.3990 | PMID = 23897955 }}
*May transform to [[diffuse large B-cell lymphoma]].
</ref>
*May transform to a more aggressive lymphoma, e.g. [[diffuse large B-cell lymphoma]].
**Prognosis after transformation significantly worse - five year survival ~ 22%.<ref name=pmid23897955/>
**Approximately 2% transform per year, or 10.7% in five years.<ref name=pmid23897955/>


==Gross==
==Gross==
48,589

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