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Difference between revisions of "Neuropathology"
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→Binswanger's disease: more
m (→Ring enhancing lesions: wikify) |
(→Binswanger's disease: more) |
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Features: | Features: | ||
*Subcortical lesions that replace the myelin consisting of macrophages. | *Subcortical lesions that replace the myelin consisting of macrophages. | ||
==Prion diseases== | |||
Etiology:<ref name=pmid16609731>{{cite journal |author=Watts JC, Balachandran A, Westaway D |title=The expanding universe of prion diseases |journal=PLoS Pathog. |volume=2 |issue=3 |pages=e26 |year=2006 |month=March |pmid=16609731 |pmc=1434791 |doi=10.1371/journal.ppat.0020026 |url=}}</ref> | |||
*Misfolded cell-surface protein called PrP(C). | |||
Includes:<ref name=pmid16609731>{{cite journal |author=Watts JC, Balachandran A, Westaway D |title=The expanding universe of prion diseases |journal=PLoS Pathog. |volume=2 |issue=3 |pages=e26 |year=2006 |month=March |pmid=16609731 |pmc=1434791 |doi=10.1371/journal.ppat.0020026 |url=}}</ref> | |||
*Creutzfeldt-Jakob disease (CJD). | |||
*Sporadic fatal insomnia (sFI). | |||
==Creutzfeldt-Jakob disease== | |||
*Commonly abbreviated as ''CJD'' | |||
*Rare. | |||
*Incurable disease. | |||
*Variant Creutzfeldt-Jakob disease (vCJD). | |||
**Associated with bovine spongiform encephalopathy | |||
===Microscopic=== | |||
Features: | |||
*??? | |||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:SpongiformChangeCJD.jpg CJD (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:VCJD_Tonsil.jpg vCJD - IHC (WC)]. | |||
==See also== | ==See also== | ||