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Difference between revisions of "Medical liver disease"
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→Primary sclerosing cholangitis
(→Hepatitis C: more) |
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*Strongly associated with [[ulcerative colitis]]; 75-90% of PSC patients have [[inflammatory bowel disease]] (IBD).<ref name=emed_psc_over>Khurana V, Singh T. Primary sclerosing cholangitis. eMedicine.com. URL: [http://emedicine.medscape.com/article/187724-overview http://emedicine.medscape.com/article/187724-overview]. Accessed on: 29 November 2009.</ref> | *Strongly associated with [[ulcerative colitis]]; 75-90% of PSC patients have [[inflammatory bowel disease]] (IBD).<ref name=emed_psc_over>Khurana V, Singh T. Primary sclerosing cholangitis. eMedicine.com. URL: [http://emedicine.medscape.com/article/187724-overview http://emedicine.medscape.com/article/187724-overview]. Accessed on: 29 November 2009.</ref> | ||
*Risk for [[cholangiocarcinoma]].<ref name=pmid19668124>{{Cite journal | last1 = Jesudian | first1 = AB. | last2 = Jacobson | first2 = IM. | title = Screening and diagnosis of cholangiocarcinoma in patients with primary sclerosing cholangitis. | journal = Rev Gastroenterol Disord | volume = 9 | issue = 2 | pages = E41-7 | month = | year = 2009 | doi = | PMID = 19668124 }}</ref> | *Risk for [[cholangiocarcinoma]].<ref name=pmid19668124>{{Cite journal | last1 = Jesudian | first1 = AB. | last2 = Jacobson | first2 = IM. | title = Screening and diagnosis of cholangiocarcinoma in patients with primary sclerosing cholangitis. | journal = Rev Gastroenterol Disord | volume = 9 | issue = 2 | pages = E41-7 | month = | year = 2009 | doi = | PMID = 19668124 }}</ref> | ||
Serology: | |||
*p-ANCA (MPO-ANCA) +ve in ~ 90% of cases.<ref name=pmid11492972>{{Cite journal | last1 = Terjung | first1 = B. | last2 = Worman | first2 = HJ. | title = Anti-neutrophil antibodies in primary sclerosing cholangitis. | journal = Best Pract Res Clin Gastroenterol | volume = 15 | issue = 4 | pages = 629-42 | month = Aug | year = 2001 | doi = 10.1053/bega.2001.0209 | PMID = 11492972 }}</ref> | |||
====Diagnosis==== | ====Diagnosis==== | ||