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Difference between revisions of "Medical kidney diseases"
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→Fabry disease: +image, format
(→Fabry disease: +image, format) |
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===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=pmid16799480>{{cite journal |author=Fischer EG, Moore MJ, Lager DJ |title=Fabry disease: a morphologic study of 11 cases |journal=Mod. Pathol. |volume=19 |issue=10 |pages=1295-301 |year=2006 |month=October |pmid=16799480 |doi=10.1038/modpathol.3800634 |url=http://www.nature.com/modpathol/journal/v19/n10/abs/3800634a.html}}</ref> | |||
*Foamy podocyte inclusions, best visualized with ''[[toluidine blue]]''. | *Foamy podocyte inclusions, best visualized with ''[[toluidine blue]]''. | ||
*Mild mesangial hypercellularity. | *Mild mesangial hypercellularity. | ||
EM:<ref name=pmid16799480/> | Images: | ||
*[http://path.upmc.edu/cases/case137/micro.html Fabry disease (upmc.edu)]. | |||
===EM=== | |||
Features:<ref name=pmid16799480/> | |||
*Myelin-like inclusions. | *Myelin-like inclusions. | ||
**Concentric bodies with an onion-skin-like appearance. | **Concentric bodies with an onion-skin-like appearance. | ||
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Note: | Note: | ||
*Myelin-like inclusion are not [http://en.wikipedia.org/wiki/Pathognomonic pathognomonic] for Fabry disease; they may result from drug use:<ref name=pmid16799480/> | *Myelin-like inclusion are not [http://en.wikipedia.org/wiki/Pathognomonic pathognomonic] for Fabry disease; they may result from drug use:<ref name=pmid16799480/> | ||
**Amiodarone | **Amiodarone. | ||
**Aminoglycosides | **Aminoglycosides. | ||
**Chloroquine. | **Chloroquine. | ||