Difference between revisions of "Salivary glands"
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(→Pleomorphic adenoma: +myoepithelioma) |
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===IHC=== | ===IHC=== | ||
*S-100 +ve, SMA +ve, GFAP +ve. | *S-100 +ve, SMA +ve, GFAP +ve. | ||
==Myoepithelioma== | |||
===General=== | |||
*Usually benign. | |||
**May be malignant. | |||
Location:<ref name=pmid2982059>{{Cite journal | last1 = Barnes | first1 = L. | last2 = Appel | first2 = BN. | last3 = Perez | first3 = H. | last4 = El-Attar | first4 = AM. | title = Myoepithelioma of the head and neck: case report and review. | journal = J Surg Oncol | volume = 28 | issue = 1 | pages = 21-8 | month = Jan | year = 1985 | doi = | PMID = 2982059 }}</ref> | |||
*Parotid gland ~50%. | |||
*Palate ~25% | |||
*Submandibular gland ~12%. | |||
Notes: | |||
*First described in 1972.<ref name=pmid5075358>{{Cite journal | last1 = Saksela | first1 = E. | last2 = Tarkkanen | first2 = J. | last3 = Wartiovaara | first3 = J. | title = Parotid clear-cell adenoma of possible myoepithelial origin. | journal = Cancer | volume = 30 | issue = 3 | pages = 742-8 | month = Sep | year = 1972 | doi = | PMID = 5075358 }}</ref> | |||
===Microsopic=== | |||
Features:<ref name=Ref_DCHH130>{{Ref DCHH|130}}</ref> | |||
*Myoepithelial cells: | |||
**May be: | |||
***Spindled. | |||
***Plasmacytoid. | |||
***Epithelioid. | |||
***Clear. | |||
*Lack of tubules. | |||
**May be upto 10% (or 5%<ref>I. Weinreb. 24 October 2011.</ref> | |||
DDx: | |||
*[[Pleomorphic adenoma]]. | |||
===IHC=== | |||
Features:<ref name=Ref_DCHH130>{{Ref DCHH|130}}</ref> | |||
*S100 +ve. | |||
*GFAP +ve. | |||
*CK14 +ve. | |||
Others:<ref name=Ref_DCHH18>{{Ref DCHH|18}}</ref> | |||
*SMA +ve. | |||
*Calponin +ve. | |||
==Basal cell adenoma== | ==Basal cell adenoma== | ||