Difference between revisions of "Germ cell tumours"

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*Most common GCT in infants and young boys.
*Most common GCT in infants and young boys.


===Microscopy===
===Microscopic===
Classic feature:
Classic feature:<ref name=Ref_PCPBoD8_510>{{Ref PCPBoD8|510}}</ref>
*Schiller-Duval bodies.
*Schiller-Duval bodies.
**Look like glomerulus - central blood vessel surrounded by epithelial-like cells a space and more epithelial-like cells
**Look like glomerulus - central blood vessel surrounded by epithelial-like cells a space and more epithelial-like cells
*Architecure - variable.
*Architecure - variable.
**Most common ''microcystic pattern''.<ref>URL: [http://webpathology.com/image.asp?case=34&n=1 http://webpathology.com/image.asp?case=34&n=1]. Accessed on: March 8, 2010.</ref>
**Most common ''microcystic pattern''<ref>URL: [http://webpathology.com/image.asp?case=34&n=1 http://webpathology.com/image.asp?case=34&n=1]. Accessed on: March 8, 2010.</ref> / lace-like pattern.
**Solid.
**Papillary.
*+/-Eosinophilic hyaline globules (contain alpha-fetoprotein).


Image:  
Notes:
*[http://www.webpathology.com/image.asp?case=34&n=5 Schiller-Duval body (webpathology.com)].
*Has a loose stroma/vaguely discohesive -- unlike embryonal carcinoma.


Variants:
Variants:
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**Vaguely resembles ''seminoma''.
**Vaguely resembles ''seminoma''.


Image:
Images:
*[http://webpathology.com/image.asp?case=34&n=6 Hepatoid Pattern].
*[http://webpathology.com/image.asp?case=34&n=6 Hepatoid Pattern (webpathology.com)].
*[http://www.webpathology.com/image.asp?case=34&n=5 Schiller-Duval body (webpathology.com)].
*[http://www.webpathology.com/image.asp?n=6&Case=34 Hyaline globules (webpathology.com)].


===IHC===
===IHC===
Retrieved from "https://librepathology.org/wiki/Germ_cell_tumours"