Difference between revisions of "Non-malignant skin disease"

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(→‎Panniculitis: split-out into separate article)
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==Panniculitis==
==Panniculitis==
DDx:
{{Main|Panniculitis}}
*Erythema nodosum.
This is dealt with in the ''[[panniculitis]]'' article.
*Erythema induratum.
 
DDx for panniculitis:
*[[Erythema nodosum]].
*[[Erythema induratum]].
*Self-inflicted trauma.
*Self-inflicted trauma.
*Systemic lupus erythematosus.
*[[Systemic lupus erythematosus]].
*Weird stuff.
*Weird stuff.
 
===Erythema nodosum===
*Most common from of panniculitis.<ref name=pmid17375516>{{Cite journal  | last1 = Schwartz | first1 = RA. | last2 = Nervi | first2 = SJ. | title = Erythema nodosum: a sign of systemic disease. | journal = Am Fam Physician | volume = 75 | issue = 5 | pages = 695-700 | month = Mar | year = 2007 | doi =  | PMID = 17375516 | URL = http://www.aafp.org/afp/2007/0301/p695.html }}</ref>
 
Causes - mnemonic ''NODOSUM'':<ref name=pmid17375516/>
*'''NO''' cause (idiopathic) ~ 55% of cases.
*'''D'''rugs (sulfonamides, amoxicillin, oral contraceptives) ~ 5% of cases.
*'''O'''ther infections - group A streptococci (streptococcal pharyngitis), Yersinia, chlamydia, mycobacteria, others ~ 30% of cases.
*[[sarcoidosis|'''S'''arcoidosis]] ~ 7% of cases.
*[[ulcerative colitis|'''U'''lcerative colitis]] & [[Crohn's disease]] ~ 2% of cases.
*'''M'''alignancy ([[leukemia]], [[Hodgkin's lymphoma]]) ~ 1% of cases
 
====Microscopic====
Features:<ref name=Ref_PBoD8_1199>{{Ref PBoD8|1199}}</ref>
*Expanded (inter-adipocyte cluster) septa.
*[[Neutrophil]]s.
*Fibrin.
 
Notes:
*No [[vasculitis]].
 
===Erythema induratum===
Features:<ref name=Ref_PBoD8_1199>{{Ref PBoD8|1199}}</ref>
*Not common.
*Etiology: unknown.
 
====Microscopic====
Features:<ref name=Ref_PBoD8_1199>{{Ref PBoD8|1199}}</ref>
*Necrotizing granulomatous inflammation.
*Necrotizing vasculitis of small/medium sized vessels (early).
 
DDx:
*Infection.


=Rare=
=Rare=
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