Difference between revisions of "Melanocytic lesions"
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| [[Spitz nevus]] (epithelioid and spindle-cell nevus) | | [[Spitz nevus]] (epithelioid and spindle-cell nevus) | ||
| long axis of nests perpendicular to surface | | long axis of nests perpendicular to surface, DE junction lesion | ||
| spindled, epithelioid or mixed melanocytes, long axis of nests perpendicular to surface, superficial mitoses common | | spindled, epithelioid or mixed melanocytes, long axis of nests perpendicular to surface, superficial mitoses common, +/-[[hyperkeratosis]], +/-[[acanthosis]], +/-[[hypergranulosis]] | ||
| Children & adolescents | | Children & adolescents | ||
| usu. non-pigmented | | usu. non-pigmented | ||
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| [[Pigmented spindle cell nevus]] of Reed (AKA Pigmented spindle cell nevus) | | [[Pigmented spindle cell nevus]] of Reed (AKA Pigmented spindle cell nevus) | ||
| nests of heavily pigmented spindle cells | | nests of heavily pigmented spindle cells, DE junction lesion | ||
| heavily pigmented spindle cells in epidermis & dermis, form " | | heavily pigmented spindle cells in epidermis & dermis, form "basket weave" pattern, well-circumscribed | ||
| women in teens & 20s; location: shoulder, pelvic girdle region | | women in teens & 20s; location: shoulder, pelvic girdle region | ||
| Pigmented +++, small size | | Pigmented +++, small size | ||
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| [[Blue nevus]] | | [[Blue nevus]] | ||
| lentil-shaped (ovoid) nests btw collagen bundles | | lentil-shaped (ovoid) nests btw collagen bundles, dermal lesion | ||
| | | lentil-shaped nests, mix of spindle or dendritic or epithelioid cell morphology, nests btw collagen | ||
| usu. head & neck or extremities; clinically confused with melanoma<ref name=Ref_PCPBoD8_592>{{Ref PCPBoD8|592}}</ref> | | usu. head & neck or extremities; clinically confused with melanoma<ref name=Ref_PCPBoD8_592>{{Ref PCPBoD8|592}}</ref> | ||
| blue flat or slightly raised lesion | | blue flat or slightly raised lesion | ||
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| [[Cellular blue nevus]] | | [[Cellular blue nevus]] | ||
| dermal lesion with pigmented spindle cells & epithelioid cells | | dermal lesion with pigmented spindle cells & epithelioid cells | ||
| deep dermis; cells lack nucleoli; biphasic: (1) epithelioid cells with pale cytoplasm, (2) pigmented spindle cells +/- melanophages | | deep dermis +/-subcutis extension; cells lack nucleoli; biphasic: (1) epithelioid cells with pale cytoplasm, (2) pigmented spindle cells +/- melanophages | ||
| congenital or acquired; usu. scalp or butt | | congenital or acquired; usu. scalp or butt | ||
| blue flat or raised lesion | | blue flat or raised lesion | ||