Difference between revisions of "Small cell lymphomas"
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==Precursor B-cell lymphoblastic lymphoma/leukemia == | ==Precursor B-cell lymphoblastic lymphoma/leukemia == | ||
===General=== | ===General=== | ||
* | *Good prognosis. | ||
*Paediatric - usu. <6 years old. | |||
===Microscopic=== | ===Microscopic=== | ||
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*CD10 +ve, TdT +ve, CD99 +ve. | *CD10 +ve, TdT +ve, CD99 +ve. | ||
*CD5 -ve. | *CD5 -ve. | ||
===Molecular=== | |||
Subclassification based on translocations:<ref name=pmid15559730>{{cite journal |author=Randolph TR |title=Advances in acute lymphoblastic leukemia |journal=Clin Lab Sci |volume=17 |issue=4 |pages=235–45 |year=2004 |pmid=15559730 |url=http://findarticles.com/p/articles/mi_qa3890/is_200410/ai_n9429273/pg_2}}</ref> | |||
* t(9;22) -- BCR-ABL | |||
* t(v;11q23) -- MLL rearrangement | |||
* t(1;19) -- E2A-PBX1 | |||
* t(12;21) -- ETV-CBF alpha | |||
==Precursor T-cell lymphoblastic lymphoma/leukemia == | ==Precursor T-cell lymphoblastic lymphoma/leukemia == | ||