Difference between revisions of "Tamoxifen"
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(Created page with "'''Tamoxifen''' is a drug that an anti-estrogen effect. It is used to treat breast cancer. The classic teaching is that it increases the risk of endometrial cancer; h...") |
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'''Tamoxifen''' is a drug that an anti-estrogen effect. It is used to treat [[breast cancer]]. | '''Tamoxifen''' is a drug that an anti-estrogen effect. It is used to treat [[breast cancer]]. | ||
The classic teaching is that it increases the risk of [[endometrial cancer]]; however, the risk is quite small<ref name=pmid19505894>{{Cite journal | last1 = Brown | first1 = K. | title = Is tamoxifen a genotoxic carcinogen in women? | journal = Mutagenesis | volume = 24 | issue = 5 | pages = 391-404 | month = Sep | year = 2009 | doi = 10.1093/mutage/gep022 | PMID = 19505894 }}</ref> or possibly negligent.<ref name=pmid19827879>{{Cite journal | last1 = Ashraf | first1 = M. | last2 = Biswas | first2 = J. | last3 = Majumdar | first3 = S. | last4 = Nayak | first4 = S. | last5 = Alam | first5 = N. | last6 = Mukherjee | first6 = KK. | last7 = Gupta | first7 = S. | title = Tamoxifen use in Indian women--adverse effects revisited. | journal = Asian Pac J Cancer Prev | volume = 10 | issue = 4 | pages = 609-12 | month = | year = | doi = | PMID = 19827879 }}</ref> | The classic teaching is that it increases the risk of [[endometrial cancer]]; however, the risk is quite small<ref name=pmid19505894>{{Cite journal | last1 = Brown | first1 = K. | title = Is tamoxifen a genotoxic carcinogen in women? | journal = Mutagenesis | volume = 24 | issue = 5 | pages = 391-404 | month = Sep | year = 2009 | doi = 10.1093/mutage/gep022 | PMID = 19505894 }}</ref> or possibly negligent.<ref name=pmid19827879>{{Cite journal | last1 = Ashraf | first1 = M. | last2 = Biswas | first2 = J. | last3 = Majumdar | first3 = S. | last4 = Nayak | first4 = S. | last5 = Alam | first5 = N. | last6 = Mukherjee | first6 = KK. | last7 = Gupta | first7 = S. | title = Tamoxifen use in Indian women--adverse effects revisited. | journal = Asian Pac J Cancer Prev | volume = 10 | issue = 4 | pages = 609-12 | month = | year = | doi = | PMID = 19827879 }}</ref> Use is also associated with [[endometrial polyp]]s. | ||
==See also== | ==See also== | ||
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[[Category:Breast pathology]] | [[Category:Breast pathology]] | ||
[[Category:Clinical]] | [[Category:Clinical]] | ||
[[Category:Drugs]] | |||