Difference between revisions of "Squamous cell carcinoma of the lung"

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**Positive in [[adenocarcinoma of the lung]].
**Positive in [[adenocarcinoma of the lung]].


SCC versus adenocarcinoma:
===SCC versus adenocarcinoma===
*p40 +ve.
*p40 +ve.
*CK5/6 +ve.
*CK5/6 +ve.
*TTF-1 -ve.
*TTF-1 -ve.
*[[Napsin]] -ve.
*[[Napsin]] -ve.
===Lung SCC versus metastatic bladder carcinoma===
As per Gruver ''et al.'':<ref name=pmid23106579>{{Cite journal  | last1 = Gruver | first1 = AM. | last2 = Amin | first2 = MB. | last3 = Luthringer | first3 = DJ. | last4 = Westfall | first4 = D. | last5 = Arora | first5 = K. | last6 = Farver | first6 = CF. | last7 = Osunkoya | first7 = AO. | last8 = McKenney | first8 = JK. | last9 = Hansel | first9 = DE. | title = Selective immunohistochemical markers to distinguish between metastatic high-grade urothelial carcinoma and primary poorly differentiated invasive squamous cell carcinoma of the lung. | journal = Arch Pathol Lab Med | volume = 136 | issue = 11 | pages = 1339-46 | month = Nov | year = 2012 | doi = 10.5858/arpa.2011-0575-OA | PMID = 23106579 }}</ref>
{| class="wikitable sortable"
! IHC
! Lung SCC
! Bladder [[urothelial carcinoma|UCC]]
|-
| CK7
| 33% +ve
| 100% +ve
|-
| CK20
| 7% +ve
| 54% +ve
|-
| GATA-3
| 23% +ve
| 78% +ve
|-
| Desmoglein-3
| 87% +ve
| 11% +ve
|-
| CK14
| 77% +ve
| 32% +ve
|-
| Uroplakin III
| 0%
| 14%
|}


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