Difference between revisions of "Adrenal gland"
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=Malignant neoplasms= | =Malignant neoplasms= | ||
==Adrenocortical carcinoma | ==Adrenocortical carcinoma== | ||
*[[AKA]] ''adrenal cortical carcinoma''. | |||
*Abbreviated ''ACC''. | |||
===General=== | |||
*Prognosis sucks. | *Prognosis sucks. | ||
===Gross=== | |||
*+/-Encapsulated. | |||
*Necrotic-appearing. | |||
Image: | |||
*[http://commons.wikimedia.org/wiki/File:Adrenal_cortical_carcinoma.JPG ACC - gross (WC)]. | |||
===Microscopic=== | ===Microscopic=== | ||
Diagnosis based on the presence of three of the following (known as ''Weiss criteria''):<ref name=pmid20551521>{{cite journal |author=Jain M, Kapoor S, Mishra A, Gupta S, Agarwal A |title=Weiss criteria in large adrenocortical tumors: a validation study |journal=Indian J Pathol Microbiol |volume=53 |issue=2 |pages=222–6 |year=2010 |pmid=20551521 |doi=10.4103/0377-4929.64325 |url=}}</ref> | |||
#High nuclear grade. | |||
#High mitotic rate. | |||
#Atypical mitoses. | |||
* | #Cleared cytoplasm in >= 25% of tumour cells. | ||
#Sheeting (diffuse architecture) in >= 1/3 of tumour cells. | |||
#Necrosis in nests. | |||
#Venous invasion. | |||
#Adrenal sinusoid invasion; lymphovascular space invasion within the adrenal gland. | |||
#Capsular invasion. | |||
Image: | |||
*[http://commons.wikimedia.org/wiki/File:Adrnal_cortical_carcinoma.JPG ACC (AFIP/WC)]. | |||
==Malignant pheochromoctyoma== | ==Malignant pheochromoctyoma== | ||