Difference between revisions of "Ballooning degeneration"

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#redirect [[Liver_pathology#Ballooning_degeneration]]
'''Ballooning degeneration''' is a histomorphologic change seen in [[liver pathology]]. It is indicative of [[steatohepatitis]].<ref name=pmid14585234>{{Cite journal  | last1 = Liangpunsakul | first1 = S | last2 = Chalasani | first2 = N | title = Treatment of Nonalcoholic Fatty Liver Disease. | journal = Curr Treat Options Gastroenterol | volume = 6 | issue = 6 | pages = 455-463 | month = Dec | year = 2003 | doi =  | PMID = 14585234 }}</ref>
 
==General==
*A form of apoptosis.<ref name=pmid17355088>{{Cite journal  | last1 = Yip | first1 = WW | last2 = Burt | first2 = AD | title = Alcoholic liver disease. | journal = Semin Diagn Pathol | volume = 23 | issue = 3-4 | pages = 149–60 | month =  | year =  2006| doi =  10.1053/j.semdp.2006.11.002| pmid = 17355088 }}</ref>
 
==Microscopic==
Features:
*Central nucleus.
**"Fat cells" have peripheral nucleus.
*Cytoplasm cleared with "whisps" or cobbwebs.
*Large relative to normal hepatocyte.
**2-3X normal size.<ref>Guindi, M. 16 September 2009.</ref>
 
Notes:
*The term is used only in conjunction with ''[[steatohepatitis]]''.
*''[[Feathery degeneration]]'' is the term used in the context of cholestasis.
**It is usually periportal.
 
DDx:
*[[Feathery degeneration]] - has noticable bile.
 
===Images===
<gallery>
Image:Ballooning_degeneration_high_mag_cropped.jpg | Ballooning degeneration. (WC/Nephron)
</gallery>
www:
*[http://www.uthscsa.edu/hscnews/EnlargePicture.asp?PicName=LiverBeforeTreatment_BODY.jpg Ballooning degeneration (uthscsa.edu)].
*[http://library.med.utah.edu/WebPath/LIVEHTML/LIVER039.html Ballooning degeneration (med.utah.edu)].
 
==See also==
*[[Feathery degeneration]].
*[[Steatohepatitis]].
*[[Steatosis]].
 
==References==
{{Reflist|2}}
 
[[Category:Liver pathology]]
Retrieved from "https://librepathology.org/wiki/Ballooning_degeneration"