Difference between revisions of "Pulmonary Langerhans cell histiocytosis"
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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = | | Image = Pulmonary Langerhans cell histiocytosis -- high mag.jpg | ||
| Width = | | Width = | ||
| Caption = | | Caption = Langerhans cell histiocytosis of the lung. [[H&E stain]]. | ||
| Synonyms = eosinophilic granuloma (of the lung) | | Synonyms = eosinophilic granuloma (of the lung) | ||
| Micro = | | Micro = cellular peribronchiolar nodules with Langerhans cells (pale staining nucleus (H&E) with nuclear infolding - "crumpled tissue paper" appearance), +/-smoker's macrophages (brown pigmented airspace macrophages), +/-eosinophilia (typical - may be rare) | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = | | LMDDx = | ||
| Stains = | | Stains = | ||
| IHC = | | IHC = Langerhans cells (CD1a +ve, S-100 +ve, CD207 +ve | ||
| EM = | | EM = | ||
| Molecular = | | Molecular = | ||
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==IHC== | ==IHC== | ||
Langerhans cells: | |||
*S100 +ve.<ref name=Ref_PPP237>{{Ref PPP|237}}</ref> | |||
*CD1a +ve.<ref name=Ref_PPP237>{{Ref PPP|237}}</ref> | |||
*CD207 (AKA Langerin) +ve | |||
==See also== | ==See also== | ||