Difference between revisions of "Squamous cell carcinoma of the urinary bladder"
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DDx: | DDx: | ||
*[[Urothelial carcinoma]] with squamous differentiation. | *[[Metastatic]] squamous cell carcinoma. | ||
**[[Squamous cell carcinoma of the uterine cervix]]. | |||
*[[Urothelial carcinoma]] with squamous differentiation - very common. | |||
**In biopsies, this should be mentioned as a possibility. | |||
*[[Condyloma acuminatum]]. | *[[Condyloma acuminatum]]. | ||
*[[Squamous dysplasia]]. | *[[Squamous dysplasia]]. | ||
==IHC== | |||
Features: | |||
*p16 -ve/+ve. | |||
**Not definite for separating from cervix - but suggestive: cervix ~86% +ve, bladder ~37% +ve.<ref name=pmid20571342>{{Cite journal | last1 = Cioffi-Lavina | first1 = M. | last2 = Chapman-Fredricks | first2 = J. | last3 = Gomez-Fernandez | first3 = C. | last4 = Ganjei-Azar | first4 = P. | last5 = Manoharan | first5 = M. | last6 = Jorda | first6 = M. | title = P16 expression in squamous cell carcinomas of cervix and bladder. | journal = Appl Immunohistochem Mol Morphol | volume = 18 | issue = 4 | pages = 344-7 | month = Jul | year = 2010 | doi = 10.1097/PAI.0b013e3181d2bbd7 | PMID = 20571342 }}</ref> | |||
==See also== | ==See also== | ||