Difference between revisions of "Neurodegenerative diseases"
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Jensflorian (talk | contribs) (→Multiple system atrophy: update) |
Jensflorian (talk | contribs) (→Alpha-synucleinopathies: +PD pictures) |
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**Eosinophilic cytoplasmic inclusion with "dense" (darker) core and pale (surrounding) halo. | **Eosinophilic cytoplasmic inclusion with "dense" (darker) core and pale (surrounding) halo. | ||
***Consist of filaments composed of alpha-synuclein. | ***Consist of filaments composed of alpha-synuclein. | ||
*Lewy neurites - alpha-synuclein positive processes. | |||
===IHC=== | ===IHC=== | ||
*Alpha-synuclein +ve. | *Alpha-synuclein +ve. | ||
===Images=== | |||
<gallery> | |||
File:Histological sample of Substantia nigra in Parkinson's disease.jpg | Lewy body (HE, left) and Lewy neurite (aSyn IHC, right). | |||
File:Lewy Body alphaSynuclein.jpg | Alpha-synculein positive Lewy body (WC/Marvin101). | |||
File:Lewy bodies (alpha synuclein inclusions).jpg | Lewy body and Lewy neurites (WC/Suraj Rajan). | |||
</gallery> | |||
==Multiple system atrophy== | ==Multiple system atrophy== | ||