Difference between revisions of "Sertoli-Leydig cell tumour"

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# Sertoli ''or'' Leydig cells.<ref name=Ref_PBoD1103>{{Ref PBoD|1103}}</ref>

#* Leydig cells:

#** Abundant solid eosinophilic cytoplasm.

#**Polygonal pink cells

#** Abundant solid or somewhat granular eosinophilic cytoplasm.

#** Round nuclei with fine chromatin and a small or indistinct [[nucleolus]].

#** Often in small clusters ~ 5-25 cells/cluster.

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# Stroma.

# +/- Sarcomatous features (mucinous glands, bone, cartilage).

*Well differentiated -

**Mature Sertoli cells line form tubules that grow in a fibrous stroma containing clusters of Leydig

cells

*Intermediate to poorly differentiated -

**A more disorganized, more cellular tumor with less mature Sertoli cells growing in trabeculae and nests. Some tubule formation, either round or retiform. Leydig cells, either singly or in clusters, are present in a cellular stroma.

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Difference between revisions of "Sertoli-Leydig cell tumour"

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@@ Line 10: / Line 10: @@
 # Sertoli ''or'' Leydig cells.<ref name=Ref_PBoD1103>{{Ref PBoD|1103}}</ref>
 #* Leydig cells:
-#** Abundant solid eosinophilic cytoplasm.
+#**Polygonal pink cells
+#** Abundant solid or somewhat granular eosinophilic cytoplasm.
 #** Round nuclei with fine chromatin and a small or indistinct [[nucleolus]].
 #** Often in small clusters ~ 5-25 cells/cluster.
@@ Line 19: / Line 20: @@
 # Stroma.
 # +/- Sarcomatous features (mucinous glands, bone, cartilage).
+*Well differentiated -
+**Mature Sertoli cells line form tubules that grow in a fibrous stroma containing clusters of Leydig
+cells
+*Intermediate to poorly differentiated -
+**A more disorganized, more cellular tumor with less mature Sertoli cells growing in trabeculae and nests.  Some tubule formation, either round or retiform. Leydig cells, either singly or in clusters, are present in a cellular stroma.
 DDx: