Difference between revisions of "Neurofibroma"

Line 50:

Features:

*Spindle cells with wavy nuclei without pleomorphism - '''key feature'''.

**Often described as "shredded carrots".

*Intermixed with wire-like collagen.

*May be arranged in fascicles and intermixed with collagen.

**Often no pattern is apparent.

**Often described as "shredded carrots".<ref name=pmid24216989>{{Cite journal | last1 = Bernthal | first1 = NM. | last2 = Jones | first2 = KB. | last3 = Monument | first3 = MJ. | last4 = Liu | first4 = T. | last5 = Viskochil | first5 = D. | last6 = Randall | first6 = RL. | title = Lost in translation: ambiguity in nerve sheath tumor nomenclature and its resultant treatment effect. | journal = Cancers (Basel) | volume = 5 | issue = 2 | pages = 519-28 | month = | year = 2013 | doi = 10.3390/cancers5020519 | PMID = 24216989 }}</ref>

*Moderate increase of cellularity vis-a-vis normal dermis.

*May be poorly or well-circumscribed.

Difference between revisions of "Neurofibroma"

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@@ Line 50: / Line 50: @@
 Features:
 *Spindle cells with wavy nuclei without pleomorphism - '''key feature'''.
-**Often described as "shredded carrots".
+*Intermixed with wire-like collagen.
-*May be arranged in fascicles and intermixed with collagen.
 **Often no pattern is apparent.
+**Often described as "shredded carrots".<ref name=pmid24216989>{{Cite journal  | last1 = Bernthal | first1 = NM. | last2 = Jones | first2 = KB. | last3 = Monument | first3 = MJ. | last4 = Liu | first4 = T. | last5 = Viskochil | first5 = D. | last6 = Randall | first6 = RL. | title = Lost in translation: ambiguity in nerve sheath tumor nomenclature and its resultant treatment effect. | journal = Cancers (Basel) | volume = 5 | issue = 2 | pages = 519-28 | month =  | year = 2013 | doi = 10.3390/cancers5020519 | PMID = 24216989 }}</ref>
 *Moderate increase of cellularity vis-a-vis normal dermis.
 *May be poorly or well-circumscribed.