Difference between revisions of "Salivary glands"
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==Carcinoma ex pleomorphic adenoma== | ==Carcinoma ex pleomorphic adenoma== | ||
*Malignant transformation of ''pleomorphic adenoma''. | *Abbreviated ''Ca ex PA''. | ||
===General=== | |||
Definition: | |||
*Malignant transformation of a ''pleomorphic adenoma''. | |||
Diagnosis (either 1 or 2): | |||
#History of a pleomorphic adenoma at the same site. | |||
#Features of a pleomorphic adenoma and a carcinoma. | |||
Epidemiology: | |||
*Rare. | *Rare. | ||
===Microscopy=== | ===Microscopy=== | ||
Features: | Features: | ||
*Nests | *Cells with cytologic features of malignancy. | ||
*Architecture (any of the following): | |||
**Glands. | |||
**Nests. | |||
**Single cells (may be subtle). | |||
Architectural patterns: | |||
*Ductal carcinoma NOS (arising from ductal cells) - most common pattern for Ca ex PA. | |||
*Myoepithelial cacinoma NOS (arising from myoepithelial cells). | |||
*"Named carcinoma": | |||
**Salivary duct carcinoma - second most common pattern for Ca ex PA. | |||
**Mucoepidermoid carcinoma. | |||
**Adenoid cystic carcinoma. | |||
Note: | Note: | ||
* | *Often adenocarcinoma-like. | ||
*Myoepithelial cells may be clear cells. (???) | |||
====Subclassification==== | |||
#Non-invasive [[AKA]] ''intracapsular'' [[AKA]] ''in situ''. | |||
#Minimally invasive <1.5 mm beyond the capsule. | |||
#Widely invasive >=1.5 mm beyond the capsule. | |||
==Sebaceous carcinoma== | ==Sebaceous carcinoma== | ||