Difference between revisions of "Basics"

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Notes:

*''Melanoma'', i.e. ''malignant melanoma'', is a separate category as it can look like almost anything under the microscope.

*''Lymphoma'' includes leukemia.

Factors to consider when attempting to group by morphology:

#Cell cohesion - dyscohesive vs. cohesive.

#*If one sees several groups of 5+ cells... probably cohesive.

#*Presence of cell cohesion strongly disfavours lymphoma.

#Cell size - in relation to a neutrophil or red blood cell.

#Cytoplasm - abundance (scant, moderate, abundant).

#*Eosinophilic cytoplasm disfavours lymphoma.

#Chromatin - coarseness (fine, granular).

#Nucleoli - number (absent, present, multiple).

#*Large nucleoli (nucleoli seen with the 10x objective) pretty much exclude neuroendocrine.

Probable category by morphology:

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@@ Line 59: / Line 59: @@
 Notes:
 *''Melanoma'', i.e. ''malignant melanoma'', is a separate category as it can look like almost anything under the microscope.
+*''Lymphoma'' includes leukemia.
 Factors to consider when attempting to group by morphology:
 #Cell cohesion - dyscohesive vs. cohesive.
 #*If one sees several groups of 5+ cells... probably cohesive.
+#*Presence of cell cohesion strongly disfavours lymphoma.
 #Cell size - in relation to a neutrophil or red blood cell.
 #Cytoplasm - abundance (scant, moderate, abundant).
+#*Eosinophilic cytoplasm disfavours lymphoma.
 #Chromatin - coarseness (fine, granular).
+#Nucleoli - number (absent, present, multiple).
+#*Large nucleoli (nucleoli seen with the 10x objective) pretty much exclude neuroendocrine.
 Probable category by morphology: