Difference between revisions of "Pancreas"
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Image: [http://jcp.bmj.com/content/61/11/1153/F1.large.jpg Solid pseudopapillary tumour (bmj.com)]. | Image: [http://jcp.bmj.com/content/61/11/1153/F1.large.jpg Solid pseudopapillary tumour (bmj.com)]. | ||
===DDx=== | ====DDx==== | ||
*Pseudocyst. | *Pseudocyst. | ||
*Cystadenoma. | *Cystadenoma. | ||
*Cystadenocarcinoma. | *Cystadenocarcinoma. | ||
===IHC=== | |||
Features:<ref>{{cite journal |author=Serra S, Chetty R |title=Revision 2: an immunohistochemical approach and evaluation of solid pseudopapillary tumour of the pancreas |journal=J. Clin. Pathol. |volume=61 |issue=11 |pages=1153–9 |year=2008 |month=November |pmid=18708424 |doi=10.1136/jcp.2008.057828 |url=http://jcp.bmj.com/content/61/11/1153}}</ref> | |||
*Beta-catenin +ve ~100% (cytoplasmic & nuclear). | |||
*E-cadherin +ve ~100% (cytoplasmic), -ve (membrane); antibody dependent. | |||
*CD10 +ve ~ 80%. | |||
*Synaptophysin +ve ~70%. | |||
*Chromogranin -ve. | |||
==Pancreatic intraepithelial neoplasia (PanIN)== | ==Pancreatic intraepithelial neoplasia (PanIN)== | ||