Difference between revisions of "Malignant melanoma"
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spread of melanocytes. Mitotic activity is seen focally. | spread of melanocytes. Mitotic activity is seen focally. | ||
</pre> | </pre> | ||
<pre> | |||
SKIN LESION, MID BACK, EXCISION: | |||
- LENTIGO MALIGNA (MELANOMA IN SITU AND SOLAR ELASTOSIS), MARGIN CLEARANCE < 0.1 MM. | |||
COMMENT: | |||
This lesion should be re-excised. | |||
</pre> | |||
====Micro==== | |||
The sections show hair-bearing skin with atypical melanocytes confined to the epidermis. | |||
The melanocytes scatter upwards (focally), have confluent growth and nucleoli, and involve | |||
the adnexal structures. Occasional large multi-nucleated melanocytes, with their nuclei | |||
arranged around the cell periphery, are present. Mitotic activity is not apparent. Extensive | |||
solar elastosis is present. | |||
The lesion is very close to the margin (<0.1 mm clearance). | |||
==See also== | ==See also== | ||