Difference between revisions of "Dermatologic neoplasms"

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Line 51: Line 51:
*[[Solar elastosis]] with ectatic [[blood vessel]]s.  
*[[Solar elastosis]] with ectatic [[blood vessel]]s.  


Images:
====Images====
*[[WC]]:
<gallery>
**[http://commons.wikimedia.org/wiki/File:Basal_cell_carcinoma_-_2_-_intermed_mag.jpg BCC - intermed. mag. (WC/Nephron)].
Image:Basal_cell_carcinoma_-_2_-_intermed_mag.jpg | BCC - intermed. mag. (WC/Nephron)
**[http://commons.wikimedia.org/wiki/File:Basal_cell_carcinoma_-_high_mag.jpg BCC - high mag. (WC/Nephron)].
Image:Basal_cell_carcinoma_-_high_mag.jpg | BCC - high mag. (WC/Nephron)
**[http://commons.wikimedia.org/wiki/File:Basal_cell_carcinoma_pathology.jpg BCC - crappy (WC)].
Image:Basal_cell_carcinoma_pathology.jpg | BCC - poor quality. (WC)
**[http://commons.wikimedia.org/wiki/File:Basal_cell_carcinoma_fibroepitheliomatous_pattern_-_very_low_mag.jpg Fibroepithelioma of Pinkus (WC/Nephron)].
Image:Basal_cell_carcinoma_fibroepitheliomatous_pattern_-_very_low_mag.jpg | Fibroepithelioma of Pinkus. (WC/Nephron)
**[http://commons.wikimedia.org/wiki/File:SkinTumors-P6040209.JPG Fibroepithelioma of Pinkus (WC)].
Image:SkinTumors-P6040209.JPG | Fibroepithelioma of Pinkus. (WC)
</gallery>
*www:
*www:
**[http://missinglink.ucsf.edu/lm/DermatologyGlossary/img/Dermatology%20Glossary/Glossary%20Histo%20Images/basal_cell_carcinoma_high_power.jpg BCC (ucsf.edu)].<ref>URL: [http://missinglink.ucsf.edu/lm/DermatologyGlossary/basal_cell_carcinoma.html http://missinglink.ucsf.edu/lm/DermatologyGlossary/basal_cell_carcinoma.html]. Accessed on: 4 September 2011.</ref>
**[http://missinglink.ucsf.edu/lm/DermatologyGlossary/img/Dermatology%20Glossary/Glossary%20Histo%20Images/basal_cell_carcinoma_high_power.jpg BCC (ucsf.edu)].<ref>URL: [http://missinglink.ucsf.edu/lm/DermatologyGlossary/basal_cell_carcinoma.html http://missinglink.ucsf.edu/lm/DermatologyGlossary/basal_cell_carcinoma.html]. Accessed on: 4 September 2011.</ref>
Line 228: Line 229:
*[[Eccrine carcinoma]].
*[[Eccrine carcinoma]].


Images:
=====Images=====
*[http://commons.wikimedia.org/wiki/File:Bowen_disease_%281%29.jpg Bowen disease - 1 (WC)].
<gallery>
*[http://commons.wikimedia.org/wiki/File:Bowen_disease_%283%29.jpg Bowen disease - 3 (WC)].
Image:Bowen_disease_%281%29.jpg | Bowen disease - 1. (WC)
 
Image:Bowen_disease_%282%29.jpg | Bowen disease - 2. (WC)
Image:Bowen_disease_%283%29.jpg | Bowen disease - 3. (WC)
</gallery>
===IHC===
===IHC===
Bowen's disease panel:
Bowen's disease panel:
Line 338: Line 341:
*[[Undifferentiated pleomorphic sarcoma]].
*[[Undifferentiated pleomorphic sarcoma]].


Images:
====Images====
*[http://commons.wikimedia.org/w/index.php?title=File:Storiform_pattern_-_intermed_mag.jpg DFSP - storiform pattern - intermed. mag. (WC)].
<gallery>
*[http://commons.wikimedia.org/wiki/File:Storiform_pattern_-_very_high_mag.jpg DFSP - storiform pattern - very high mag. (WC)].
Image:Storiform_pattern_-_intermed_mag.jpg | DFSP - storiform pattern - intermed. mag. (WC/Nephron)
Image:Storiform_pattern_-_very_high_mag.jpg | DFSP - storiform pattern - very high mag. (WC/Nephron)
</gallery>
www:
*[http://webpathology.com/image.asp?case=317&n=1 DFSP (webpathology.com)].
*[http://webpathology.com/image.asp?case=317&n=1 DFSP (webpathology.com)].


Line 396: Line 402:
*[[Lymphomatoid papulosis]].
*[[Lymphomatoid papulosis]].


Images:
====Images====
*[http://commons.wikimedia.org/wiki/File:Cutaneous_T-cell_lymphoma_-_very_high_mag.jpg CTCL - very high mag. (WC)].
<gallery>
*[http://commons.wikimedia.org/wiki/File:Cutaneous_T-cell_lymphoma_-_intermed_mag.jpg CTCL - intermed. mag. (WC)].
Image:Cutaneous_T-cell_lymphoma_-_very_high_mag.jpg | CTCL - very high mag. (WC/Nephron)
Image:Cutaneous_T-cell_lymphoma_-_intermed_mag.jpg | CTCL - intermed. mag. (WC/Nephron)
</gallery>
www:
*[http://www.jci.org/articles/view/24826/figure/2 CTCL (jci.org)].
*[http://www.jci.org/articles/view/24826/figure/2 CTCL (jci.org)].
*[http://www.mdconsult.com/das/book/body/199872830-2/0/1709/I4-u1.0-B978-0-443-06694-8..50117-2--f2.fig CTCL (mdconsult.com)].
*[http://www.mdconsult.com/das/book/body/199872830-2/0/1709/I4-u1.0-B978-0-443-06694-8..50117-2--f2.fig CTCL (mdconsult.com)].
Line 456: Line 465:
*Other [[small round cell tumours]].
*Other [[small round cell tumours]].


Images:
====Images====
*www:
<gallery>
**[http://www.bccancer.bc.ca/HPI/CE/cytotechnology/cytosleuthquiz/nongyne/ng12hist.htm MCC (bccancer.bc.ca)].
Image:Merkel_cell_carcinoma_-_intermed_mag.jpg | MCC - intermed. mag. (WC/Nephron)
**[http://www.joplink.net/prev/200403/07.html MCC (joplink.net)].
Image:Merkel_cell_carcinoma_-_very_high_mag.jpg | MCC - very high mag. (WC/Nephron)
**[http://www.ispub.com/ispub/ijd/volume_5_number_2_8/concurrent_merkel_cell_carcinoma_and_bowen_s_disease_of_the_thigh/bowen-fig3.jpg Merkel cell carcinoma (ispub.com)].
Image:Merkelcellcarcinoma_Tag.jpg | Merkel cell carcinoma - nested pattern (WC)
**[http://path.upmc.edu/cases/case398.html Merkel cell carcinoma - several images (upmc.edu)].
</gallery>
*[[WC]]:
www:
**[http://commons.wikimedia.org/wiki/File:Merkel_cell_carcinoma_-_intermed_mag.jpg MCC - intermed. mag. (WC)].
*[http://www.bccancer.bc.ca/HPI/CE/cytotechnology/cytosleuthquiz/nongyne/ng12hist.htm MCC (bccancer.bc.ca)].
**[http://commons.wikimedia.org/wiki/File:Merkel_cell_carcinoma_-_very_high_mag.jpg MCC - very high mag. (WC)].
*[http://www.joplink.net/prev/200403/07.html MCC (joplink.net)].
**[http://commons.wikimedia.org/wiki/File:Merkelcellcarcinoma_Tag.jpg Merkel cell carcinoma - nested pattern (WC)].
*[http://www.ispub.com/ispub/ijd/volume_5_number_2_8/concurrent_merkel_cell_carcinoma_and_bowen_s_disease_of_the_thigh/bowen-fig3.jpg Merkel cell carcinoma (ispub.com)].
*[http://path.upmc.edu/cases/case398.html Merkel cell carcinoma - several images (upmc.edu)].


===IHC===
===IHC===
Line 536: Line 546:
*[[Sweat gland carcinoma]].
*[[Sweat gland carcinoma]].


Images:
====Images====
*www:
<gallery>
**[http://www.ispub.com/journal/the-internet-journal-of-otorhinolaryngology/volume-9-number-2/sebaceous-adenocarcinoma-of-the-parotid-gland-a-case-report-and-literature-review.article-g01.fs.jpg Sebaceous carcinoma (ispub.com)].<ref name=Warman>URL: [http://www.ispub.com/journal/the_internet_journal_of_otorhinolaryngology/volume_9_number_2_11/article/sebaceous_adenocarcinoma_of_the_parotid_gland_a_case_report_and_literature_review.html http://www.ispub.com/journal/the_internet_journal_of_otorhinolaryngology/volume_9_number_2_11/article/sebaceous_adenocarcinoma_of_the_parotid_gland_a_case_report_and_literature_review.html]. Accessed on: 8 September 2011.</ref>
Image:Sebaceous_carcinoma_-_intermed_mag.jpg | Sebaceous carcinoma - intermed. mag. (WC/Nephron)
*[[WC]]:
Image:Sebaceous_carcinoma_-_very_high_mag.jpg | Sebaceous carcinoma - very high mag. (WC/Nephron)
**[http://commons.wikimedia.org/wiki/File:Sebaceous_carcinoma_-_intermed_mag.jpg Sebaceous carcinoma - intermed. mag. (WC)].
</gallery>
**[http://commons.wikimedia.org/wiki/File:Sebaceous_carcinoma_-_very_high_mag.jpg Sebaceous carcinoma - very high mag. (WC)].
www:
*[http://www.ispub.com/journal/the-internet-journal-of-otorhinolaryngology/volume-9-number-2/sebaceous-adenocarcinoma-of-the-parotid-gland-a-case-report-and-literature-review.article-g01.fs.jpg Sebaceous carcinoma (ispub.com)].<ref name=Warman>URL: [http://www.ispub.com/journal/the_internet_journal_of_otorhinolaryngology/volume_9_number_2_11/article/sebaceous_adenocarcinoma_of_the_parotid_gland_a_case_report_and_literature_review.html http://www.ispub.com/journal/the_internet_journal_of_otorhinolaryngology/volume_9_number_2_11/article/sebaceous_adenocarcinoma_of_the_parotid_gland_a_case_report_and_literature_review.html]. Accessed on: 8 September 2011.</ref>


====Grading====
====Grading====
Line 780: Line 791:
*[[Basal cell carcinoma]] - has [[myxoid stroma]].
*[[Basal cell carcinoma]] - has [[myxoid stroma]].


Images:
====Images====
*[[WC]]:
<gallery>
**[http://commons.wikimedia.org/wiki/File:Dermal_cylindroma_intermed_mag.jpg Dermal cylindroma (WC)].
Image:Dermal_cylindroma_intermed_mag.jpg | Dermal cylindroma. (WC/Nephron)
**[http://commons.wikimedia.org/wiki/File:Dermal_cylindroma_intermed_mag_deep.jpg Dermal cylindroma - high mag. (WC)].
Image:Dermal_cylindroma_intermed_mag_deep.jpg | Dermal cylindroma - high mag. (WC/Nephron)
*www:
</gallery>
**[http://jcp.bmj.com/content/60/2/145/F7.large.jpg Dermal cylindroma (bmj.com)].<ref name=pmid16882695>{{Cite journal  | last1 = Obaidat | first1 = NA. | last2 = Alsaad | first2 = KO. | last3 = Ghazarian | first3 = D. | title = Skin adnexal neoplasms--part 2: an approach to tumours of cutaneous sweat glands. | journal = J Clin Pathol | volume = 60 | issue = 2 | pages = 145-59 | month = Feb | year = 2007 | doi = 10.1136/jcp.2006.041608 | PMID = 16882695 | PMC = 1860616 | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1860616/?tool=pubmed }}</ref>
www:
*[http://jcp.bmj.com/content/60/2/145/F7.large.jpg Dermal cylindroma (bmj.com)].<ref name=pmid16882695>{{Cite journal  | last1 = Obaidat | first1 = NA. | last2 = Alsaad | first2 = KO. | last3 = Ghazarian | first3 = D. | title = Skin adnexal neoplasms--part 2: an approach to tumours of cutaneous sweat glands. | journal = J Clin Pathol | volume = 60 | issue = 2 | pages = 145-59 | month = Feb | year = 2007 | doi = 10.1136/jcp.2006.041608 | PMID = 16882695 | PMC = 1860616 | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1860616/?tool=pubmed }}</ref>


===Stains===
===Stains===
Line 817: Line 829:
*[[Pseudoepitheliomatous hyperplasia]].
*[[Pseudoepitheliomatous hyperplasia]].


Image:
====Image====
*[http://commons.wikimedia.org/wiki/File:Skin_keratoacanthoma_whole_slide.jpg Keratocanthoma (WC).]
<gallery>
 
Image:Skin_keratoacanthoma_whole_slide.jpg | Keratocanthoma. (WC)
</gallery>
==Sebaceous adenoma==
==Sebaceous adenoma==
===General===
===General===
Line 833: Line 846:
**Multiple dilated glands - opening to the surface.
**Multiple dilated glands - opening to the surface.


Images:
====Images====
*www:
<gallery>
**[http://dermatlas.med.jhmi.edu/derm/indexDisplay.cfm?ImageID=587283984 Sebaceous adenoma (jhmi.edu)].
Image:Sebaceous_adenoma_-_low_mag.jpg | Sebaceous adenoma - low mag. (WC/Nephron)
*[[WC]]:
Image:Sebaceous_adenoma_-_high_mag.jpg | Sebaceous adenoma - high mag. (WC/Nephron)
**[http://commons.wikimedia.org/wiki/File:Sebaceous_adenoma_-_low_mag.jpg Sebaceous adenoma - low mag. (WC)].
</gallery>
**[http://commons.wikimedia.org/wiki/File:Sebaceous_adenoma_-_high_mag.jpg Sebaceous adenoma - high mag. (WC)].
www:
*[http://dermatlas.med.jhmi.edu/derm/indexDisplay.cfm?ImageID=587283984 Sebaceous adenoma (jhmi.edu)].


==Trichilemmoma==
==Trichilemmoma==
Line 916: Line 930:
*[[Eccrine poroma]].
*[[Eccrine poroma]].


Images:
====Images====
*[http://commons.wikimedia.org/wiki/File:Nodular_hidradenoma_-_low_mag.jpg Nodular hidradenoma - low mag. (WC)].
<gallery>
*[http://commons.wikimedia.org/wiki/File:Nodular_hidradenoma_-_intermed_mag.jpg Nodular hidradenoma - intermed. mag. (WC)].
Image:Nodular_hidradenoma_-_low_mag.jpg | Nodular hidradenoma - low mag. (WC/Nephron)
*[http://commons.wikimedia.org/wiki/File:Nodular_hidradenoma_-_very_high_mag.jpg Nodular hidradenoma - very high mag. (WC)].
Image:Nodular_hidradenoma_-_intermed_mag.jpg | Nodular hidradenoma - intermed. mag. (WC/Nephron)
 
Image:Nodular_hidradenoma_-_very_high_mag.jpg | Nodular hidradenoma - very high mag. (WC/Nephron)
</gallery>
===IHC===
===IHC===
Features:<ref name=pmid9537017/>
Features:<ref name=pmid9537017/>
Line 959: Line 974:
*[[Sebaceous carcinoma]], well-differentiated - has some cells with clear vacuolated cytoplasm.
*[[Sebaceous carcinoma]], well-differentiated - has some cells with clear vacuolated cytoplasm.


Images:
===Images====
*[[WC]]:
<gallery>
**[http://commons.wikimedia.org/wiki/File:Trichoepithelioma_-_low_mag.jpg Trichoepithelioma - low mag. (WC)].
Image:Trichoepithelioma_-_low_mag.jpg | Trichoepithelioma - low mag. (WC/Nephron)
**[http://commons.wikimedia.org/wiki/File:Trichoepithelioma_-_high_mag.jpg Trichoepithelioma - high mag. (WC)].
Image:Trichoepithelioma_-_high_mag.jpg | Trichoepithelioma - high mag. (WC/Nephron)
*www:
</gallery>
**[http://img.medscape.com/pi/emed/ckb/dermatology/1048885-1055824-1060049-1348744.jpg Papillary-mesenchymal body (medscape.com)].<ref>URL: [http://emedicine.medscape.com/article/1060049-workup#a0723 http://emedicine.medscape.com/article/1060049-workup#a0723 Papillary-mesenchymal body (emedicine.medscape.com)]. Accessed on: 22 August 2012.</ref>
www:
**[http://skinpathologyatlas.com/tumors/hair/images/trichofollic-20x-pal.jpg Papillary-mesenchymal body (skinpathologyatlas.com)].<ref>URL: [http://skinpathologyatlas.com/tumors/hair/trichofollic.htm http://skinpathologyatlas.com/tumors/hair/trichofollic.htm]. Accessed on: 22 August 2012.</ref>
*[http://img.medscape.com/pi/emed/ckb/dermatology/1048885-1055824-1060049-1348744.jpg Papillary-mesenchymal body (medscape.com)].<ref>URL: [http://emedicine.medscape.com/article/1060049-workup#a0723 http://emedicine.medscape.com/article/1060049-workup#a0723 Papillary-mesenchymal body (emedicine.medscape.com)]. Accessed on: 22 August 2012.</ref>
**[http://www.dermnetnz.org/common/image.php?path=/pathology/img/t/trichoepitheliomafigure3.jpg Trichoepithelioma (dermnetnz.org)].
*[http://skinpathologyatlas.com/tumors/hair/images/trichofollic-20x-pal.jpg Papillary-mesenchymal body (skinpathologyatlas.com)].<ref>URL: [http://skinpathologyatlas.com/tumors/hair/trichofollic.htm http://skinpathologyatlas.com/tumors/hair/trichofollic.htm]. Accessed on: 22 August 2012.</ref>
*[http://www.dermnetnz.org/common/image.php?path=/pathology/img/t/trichoepitheliomafigure3.jpg Trichoepithelioma (dermnetnz.org)].


===Sign out===
===Sign out===
Line 999: Line 1,015:
*[[Basal cell carcinoma]].
*[[Basal cell carcinoma]].


Images:
====Images====
www:
*[http://www.dermatopathonline.com/trichofolliculoma2.html Trichofolliculoma - several images (dermatopathonline.com)].
*[http://www.dermatopathonline.com/trichofolliculoma2.html Trichofolliculoma - several images (dermatopathonline.com)].
*[http://commons.wikimedia.org/wiki/File:SkinTumors-P6190340.JPG Trichofolliculoma (WC)]. (???)
<gallery>
 
Image:SkinTumors-P6190340.JPG | Trichofolliculoma. (WC)
</gallery>
==Apocrine carcinoma of the skin==
==Apocrine carcinoma of the skin==
===General===
===General===
Line 1,016: Line 1,034:
*[[Paget disease of the breast]]/[[Extramammary Paget disease]].
*[[Paget disease of the breast]]/[[Extramammary Paget disease]].


Images:
====Images====
*[http://commons.wikimedia.org/wiki/File:Apocrine_carcinoma_-_intermed_mag.jpg Apocrine carcinoma - intermed. mag. (WC)].
<gallery>
*[http://commons.wikimedia.org/wiki/File:Apocrine_carcinoma_-_high_mag.jpg Apocrine carcinoma - high mag. (WC)].
Image:Apocrine_carcinoma_-_intermed_mag.jpg | Apocrine carcinoma - intermed. mag. (WC/Nephron)
 
Image:Apocrine_carcinoma_-_high_mag.jpg | Apocrine carcinoma - high mag. (WC/Nephron)
</gallery>
===Stains===
===Stains===
Features:<ref name=pmid7678545/>
Features:<ref name=pmid7678545/>